Basic information
- CAS
21848-62-4- Standard SMILES
COc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1[C@H](C2)NCC3- InChIKey
MZSUVQFIWWXTFR-AWEZNQCLSA-N- Molecular formula
- C20H23NO4
- Average molar mass
- 341.4 g/mol
- Monoisotopic mass
- 341.16270821
Overview
Norglaucin is an isoquinoline alkaloid.
Names & identifiers
- Preferred name
- Norglaucine
- IUPAC
- (6aS)-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
- English name
- [6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-4H-dibenzo[de,g]quinoline
- Molecular formula
- C20H23NO4
- Molecular weight
- 341.4
Names & synonyms
Norglaucine21848-62-4Laurelliptine, O,O'-dimethyl-DTXSID00176254RefChem:1092583DTXCID7098745Norglaucin(6aS)-1,2,9,10-tetramethoxy-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolined-N-Norglaucine(+)-N-NorglaucineO,O-Dimethyllaurelliptine1,2,9,10-Tetramethoxy-6a-alpha-noraporphine
Show more names
Demeglaucine(6aS)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-4H-dibenzo[de,g]quinoline4H-Dibenzo[de,g]quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-, (6aS)-[6aS,(+)]-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-4H-dibenzo[de,g]quinoline
6a-alpha-NORAPORPHINE, 1,2,9,10-TETRAMETHOXY-orb1680032CHEBI:181571MZSUVQFIWWXTFR-AWEZNQCLSA-NHY-N9339AKOS040763720Laurelliptine, O,O'-dimethyl- (7CI)4H-Dibenzo(de,g)quinoline, 5,6,6a,7-tetrahydro-1,2,9,10-tetramethoxy-, (S)-
Database identifiers
- CAS
21848-62-4
Properties
Computed structural properties
- XLogP
- 2.9
- Topological polar surface area
- 49 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 25
- Formal charge
- 0
- Complexity
- 461
Physicochemical properties
- Boiling point
- 477.03 °C · 477.03°C (rough estimate)
- Density
- 1.2064 · 1.2064 (rough estimate)
- refractive index
- 1.5614 · 1.5614 (estimate)
- pka
- 7.14 · 7.14±0.20(Predicted)
- color
- Noncrystalline solid
- Toxicity
- 50 orl-mus: · LD50 orl-mus: 450 mg/kg APFRAD 38,537,80
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 orl-mus: 450 mg/kg APFRAD 38,537,80
Chemistry & industry
Applications
UsesNorglaucine ((+)-Norglaucine), a cytotoxic alkaloid, exhibitscytotoxicity towards the tumor cell lines B16-F10, HepG2, K562 and HL-60 cells[1].
Suppliers6 total
武汉市皇臻生物化工有限公司13795480948 · [email protected]
成都格利普生物科技有限公司028-87075086 18030859262 · [email protected]
成都格利普生物科技有限公司028-87075086 13350802083 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
成都格普特生物科技有限公司13881890404 · [email protected]
成都普菲德对照品科技有限公司028-82610909 15882229804 · [email protected]
Additional notes
DefinitionChEBI: Norglaucin is an isoquinoline alkaloid.
Related reactions
1 records
Compound notes
Loading…