Basic information
- CAS
23256-42-0- Standard SMILES
CC(O)C(=O)O.COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC- InChIKey
IIZVTUWSIKTFKO-UHFFFAOYSA-N- Molecular formula
- C17H24N4O6
- Average molar mass
- 380.4 g/mol
Names & identifiers
- Preferred name
- Trimethoprim lactate
- IUPAC
- 2-hydroxypropanoic acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- English name
- Trimethoprim lactate salt
- Molecular formula
- C17H24N4O6
- Molecular weight
- 380.4
Names & synonyms
23256-42-0TRIMETHOPRIM LACTATELACTOTRIMUNII-P3K8GP9FDQP3K8GP9FDQEINECS 245-533-1TRIMETHOPRIM LACTATE [WHO-DD]2,4-PYRIMIDINEDIAMINE, 5-((3,4,5-TRIMETHOXYPHENYL)METHYL)-, MONO(2-HYDROXYPROPANOATE)RefChem:191738245-533-1Trimethoprim lactate saltTrimethoprim lactic Acid
Show more names
Lactic triMethopriMLactic acid trimethoprim5-(3,4,5-Trimethoxybenzyl)Trimethylolpropane lactateTrimethoprim lactate, >=99%Trimethoprim lactate salt USP/EP/BPTrimethoprim lactate salt /Lactate TMP
5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoateTrimethoprim (lactate)MLS000069832Wellcoprim (TN)2-oxidanylpropanoic acidOpera_ID_7052-hydroxypropanoic acid;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamineMFCD00171722
Database identifiers
- CAS
23256-42-0- PubChem CID
- 3084396
- DTXSID
DTXSID00945947- ChEMBL
CHEMBL1430611- UNII
- P3K8GP9FDQ
- EC Number
- 245-533-1
Properties
Computed structural properties
- Topological polar surface area
- 163 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 6
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 366
Experimental & physicochemical properties
Solubility>57.1 [ug/mL] (The mean of the results at pH 7.4)
Physicochemical properties
- Melting point
- 170 · 170 - 172°C
- storage temp.
- 2 · Keep in dark place,Inert atmosphere,2-8°C
- solubility
- 2 O: · H2O: soluble20mg/mL
- form
- powder
- color
- white
- Water Solubility
- Soluble in water
- InChI
- InChI=1S/C14H18N4O3.C3H6O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15;1-2(4)3(5)6/h5-7H,4H2,1-3H3,(H4,15,16,17,18);2,4H,1H3,(H,5,6)
- InChIKey
- IIZVTUWSIKTFKO-UHFFFAOYSA-N
- SMILES
- C(O)(C)C(=O)O.C(C1=CN=C(N)N=C1N)C1C=C(OC)C(OC)=C(OC)C=1
- CAS DataBase Reference
- 23256 · 23256-42-0(CAS DataBase Reference)
- FDA UNII
- 3 K8GP9FDQ · P3K8GP9FDQ
- UNSPSC Code
- 51285203 · 51285203
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 40% (2 of 5) of reports.
Danger
H301 (40%): Toxic if swallowed [Danger Acute toxicity, oral]
P203, P261, P262, P264, P270, P271, P272, P280, P301+P316, P301+P317, P302+P352, P304+P340, P316, P317, P318, P321, P330, P333+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 5 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory InformationTrimethoprim lactate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesAcute Tox. 3 (40%)
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- ridadr
- UN 2811
- risk_code
- 23/24/25-43-61
- Signal word
- Danger
- Symbol(GHS)
- GHS06,GHS08
- hazard_code
- T
- safety_code
- 22-36/37/39-45-53
- hazard_class
- 6.1(b)
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- packing_group
- III
- Hazard statements
- H301-H361d
- Hazard Classifications
Chemistry & industry
Applications
UsesTrimethoprim lactate salt is an antibacterial agent.
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
湖北金梭生物科技有限公司00123456789 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
上海弘顺生物科技有限公司15901914505 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
湖北辰心化工有限公司18696113233 · [email protected]
江西瑞威尔生物科技有限公司400-880-2824 18107960669 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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