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Basic information
- CAS
60398-23-4- Standard SMILES
NC(N)=NC(=O)c1nc(I)c(N)nc1N- InChIKey
FKXYVYMLZGVJIM-UHFFFAOYSA-N- Molecular formula
- C6H8IN7O
- Average molar mass
- 321.082 g/mol
- Monoisotopic mass
- 320.98350588
Names & identifiers
- Preferred name
- 6-Iodoamiloride
- IUPAC
- 3,5-Diamino-N-(diaminomethylidene)-6-iodopyrazine-2-carboxamide
- English name
- 6-Iodoamiloride,hydrochloridedihydrate
- Molecular formula
- C6H8IN7O
- Molecular weight
- 321.08
Names & synonyms
6-iodoamiloride6-Iodoamiloride,HCldihydrate3,5-Diamino-6-iodo-N-(aminoiminomethyl)pyrazine-2-carboxamide2-Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-iodo-
Database identifiers
- CAS
60398-23-4- PubChem CID
- 3085183
- DTXSID
DTXSID80209150- ChEMBL
CHEMBL1909813、CHEMBL1962825- Nikkaji
- J344.125C
Chemistry & industry
Applications
Uses6-Iodoamiloride is a potent acid-sensing ion channel 1 (ASIC1) inhibitor with an IC50 of 88 nM. 6-Iodoamiloride inhibits ASIC3-mediated currents from rat dorsal root ganglion neurons with an IC50 of 230 nM[1].
Suppliers2 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
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Compound notes
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