Basic information
- CAS
1083-09-6- Standard SMILES
COc1cc(OC)c(OC)cc1CC(C)N- InChIKey
TVSIMAWGATVNGK-UHFFFAOYSA-N- Molecular formula
- C12H19NO3
- Average molar mass
- 225.28 g/mol
- Monoisotopic mass
- 225.13649347
Overview
RN given refers to parent cpd; structure
Names & identifiers
- Preferred name
- 2,4,5-Trimethoxyamphetamine
- IUPAC
- 1-(2,4,5-trimethoxyphenyl)propan-2-amine
- English name
- 2,4,5-TRIMETHOXYAMPHETAMIN
- Molecular formula
- C12H19NO3
- Molecular weight
- 225.29
Names & synonyms
2,4,5-Trimethoxyamphetamine1083-09-62,4,5-Trimethoxyphenylisopropylamine713Z3SL0TJ2,4,5-Trimethoxy-alpha-methylbenzeneethanaminePhenethylamine, 2,4,5-trimethoxy-alpha-methyl-DTXSID00874364TMA-2 cpdRefChem:908691DTXCID0010124921-(2,4,5-trimethoxyphenyl)propan-2-amineTMA-2
Show more names
2,4,5-TMATMA-2 USP/EP/BP2,4,5-TRIMETHOXYAMPHETAMIN, >99% (HPLC)1-(2,4,5-Trimethoxyphenyl)-2-propanamine2,4,5-Trimethoxy-α-methylbenzeneethanamineα-Methyl-2,4,5-trimethoxybenzeneethanamine
2,4,5-TRIMETHOXYAMPHETAMIN2,4,5-Trimethoxy-alpha-methylphenethylaminePhenethylamine, 2,4,5-trimethoxy-.alpha.-methyl-CHEMBL8389Phenethylamine, .alpha.-methyl-2,4,5-trimethoxy-UNII-713Z3SL0TJPhenethylamine, alpha-methyl-2,4,5-trimethoxy-J13.143A
Database identifiers
- CAS
1083-09-6、22199-15-1- PubChem CID
Properties
Computed structural properties
- XLogP
- 1.7
- Topological polar surface area
- 53.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 5
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 201
Experimental & physicochemical properties
Drugs
DEA NFLIS-Drug Category -> Phenethylamines (Amphetamines) (H)
Pharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds
LogP1.74
Physicochemical properties
- Melting point
- 130 °C · 130 °C
- Boiling point
- 329.5 · 329.5±37.0 °C(Predicted)
- Density
- 1.048 · 1.048±0.06 g/cm3(Predicted)
- solubility
- 20 mg/ml; · DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
- pka
- 9.54 · 9.54±0.10(Predicted)
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 713 Z3SL0TJ · 713Z3SL0TJ
Chemistry & industry
Applications
UsesTMA-2, known more formally as 2,4,5-trimethoxy-amphetamine, is a psychedelic hallucinogen which has appeared on the illicit drug market. Unlike amphetamines and cathinones, TMA-2 has no effect on monoamine re-uptake. TMA has modest effects on the 5-HT2 serotonin receptors (pEC50 values of 5.15 and 5.31 M for phosphatidylinositol release through 5-HT2A and 5HT2C, respectively). This product is intended for research and forensic applications.[Cayman Chemical]
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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