Basic information
- CAS
85797-13-3- Standard SMILES
NC(CCCCCP(=O)(O)O)C(=O)O- InChIKey
MYDMWESTDPJANS-UHFFFAOYSA-N- Molecular formula
- C7H16NO5P
- Average molar mass
- 225.18 g/mol
- Monoisotopic mass
- 225.07660961
Overview
(D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation
Names & identifiers
- Preferred name
- 2-Amino-7-phosphonoheptanoic acid
- IUPAC
- 2-amino-7-phosphonoheptanoic acid
- English name
- (+/-)-2-Amino-7-phosphonoheptanoic
- Molecular formula
- C7H16NO5P
- Molecular weight
- 225.18
Names & synonyms
2-Amino-7-phosphonoheptanoic acid85797-13-3P34K80CUSMDTXSID501017823AP-7 compound2-amino-7-phosphoheptanoic acidRefChem:85336DTXCID101427135(+--)-2-amino-7-phosphonoheptanoic acidDL-AP778966-69-5AP-7
Show more names
Brn 35441522-amino-7-phosphono-heptanoicaci
DL-2-Amino-7-phosphonoheptanoic acidNSC672105(+/-)-2-Amino-7-phosphonoheptanoic acidCHEMBL274440(+/-)-2-AMINO-7-PHOSPHONOHEPTANOIC2-Amino-7-phosphono-heptanoic acidUNII-P34K80CUSMHeptanoic acid, 2-amino-7-phosphono-
Database identifiers
- CAS
85797-13-3- PubChem CID
- 3122
- DTXSID
DTXSID501017823- ChEMBL
CHEMBL274440- UNII
- P34K80CUSM
- Nikkaji
- J33.382D
Properties
Computed structural properties
- XLogP
- -3.6
- Topological polar surface area
- 121 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 7
- Heavy atoms
- 14
- Formal charge
- 0
- Complexity
- 226
Physicochemical properties
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 34 K80CUSM · P34K80CUSM
- Safety Statements
- 22 · 22-24/25
- RTECS
- 1927500 · MJ1927500
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- rtecs
- MJ1927500
- safety_code
- 22-24/25
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used to prevent SEIZURES or reduce their severity.
Drugs that bind to but do not activate excitatory amino acid receptors, thereby blocking the actions of agonists.
Applications
UsesDL-AP7 is a competitive NMDA antagonist and an anticonvulsant. DL-AP7 blocks the NMDA-induced convulsions and impairs learning performance in a passive avoidance task in mice[1].
Suppliers7 total
T&W GROUP021-61551611 13296011611 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
3 records
Compound notes
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