2-Amino-thiazole-5-carboxylic acid ethyl ester

HCID 314628CAS 32955-21-8
Substructure searchFind similar structures

Basic information

Standard SMILES
CCOC(=O)c1cnc(N)s1
InChIKey
VNZXERIGKZNEKB-UHFFFAOYSA-N
Molecular formula
C6H8N2O2S
Average molar mass
172.21 g/mol
Monoisotopic mass
172.0306485

Names & identifiers

Preferred name
2-Amino-thiazole-5-carboxylic acid ethyl ester
IUPAC
ethyl 2-amino-1,3-thiazole-5-carboxylate
English name
Ethyl 2-aminothiazole-5-carboxylate
Molecular formula
C6H8N2O2S
Molecular weight
172.2

Names & synonyms

2-amino-thiazole-5-carboxylic acid ethyl esterRefChem:465078676-105-6Ethyl 2-aminothiazole-5-carboxylate32955-21-8ethyl 2-amino-1,3-thiazole-5-carboxylateEthyl 2-amino-thiazole-5-carboxylateMFCD006021392-aminothiazole-5-carboxylic acid ethyl ester5-thiazolecarboxylic acid, 2-amino-, ethyl ester2-AMINO-5-THIAZOLECARBOXYLIC ACID ETHYL ESTERethyl2-aminothiazole-5-carboxylate
Show more names
BUTTPARK 77\50-04RARECHEM AL BI 12632-aMinothiazole-5-EthylETHYL 2-AMINO-5-CARBOXLATE2-aMino-5-thiazolecarboxylateEthyl-2-aminothiazole-5-carbonylateEthyl 2-amino-5-thiazolecarboxylateethyl 2-Aminothiozole-5-carboxylate2-AMINOTHIAZOLE-5-ETHYL CARBOXYLATE
2-Amino-5-(ethoxycarbonyl)thiazole; 2-Aminothiazole-5-carboxylic Acid Ethyl Ester; Ethyl 2-Amino-1,3-thiazole-5-carboxylate; Ethyl 2-Amino-5-thiazolecarboxylate; NSC 233051NSC233051Oprea1_514496SCHEMBL222203orb2940535ethyl 2-aminothiazole-5-formateSCHEMBL25002942DTXSID30310861

Database identifiers

CAS
32955-21-8
PubChem CID
314628
DTXSID
DTXSID30310861
EC Number
676-105-6
Nikkaji
J1.483.001D

Properties

Computed structural properties

XLogP
1.2
Topological polar surface area
93.5 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
5
Rotatable bonds
3
Heavy atoms
11

Physicochemical properties

Melting point
144 · 144-148
Boiling point
308 · 308.0±15.0 °C(Predicted)
Density
1.336 · 1.336±0.06 g/cm3(Predicted)
storage temp.
2 · 2-8°C
Water Solubility
Insoluble in water
form
powder to crystal

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H302+H312+H332 (20%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 5 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (20%)

Safety data

PPE
Eyeshields, Gloves, type N95 (US)
wgk
2
hs_code
29339900
risk_code
36/37/38
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Applications

Uses2-Amino-5-thiazolecarboxylic Acid Ethyl Ester is used in the synthesis of dual-action antidiabetic agents that inhibit glycogen phosphorylase.

Upstream & downstream products

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
常熟市海天医药原料有限公司13913622609
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]

Related reactions

101 records
New reaction record

Linked notes

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