Basic information
- CAS
30100-83-5- Standard SMILES
O=C1CCN(C2OC(CO)C(O)C2O)C(=O)N1- InChIKey
ZPTBLXKRQACLCR-UHFFFAOYSA-N- Molecular formula
- C9H14N2O6
- Average molar mass
- 246.22 g/mol
- Monoisotopic mass
- 246.08518617
Names & identifiers
- Preferred name
- Uridine, 5,6-dihydro-
- IUPAC
- 1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione
- English name
- 5,6-Dihydro-ara-uridine
- Molecular formula
- C9H14N2O6
- Molecular weight
- 246.22
Names & synonyms
30100-83-5Uridine, 5,6-dihydro-DTXSID10313719RefChem:203427DTXCID602648435,6-Dihydro-ara-uridine1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dioneC9H14N2O6SCHEMBL18512842NSC275645NSC791649NSC-275645
Show more names
2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyldihydro-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)dihydropyrimidine-2,4(1H,3H)-dione
NSC-791649FD1448691-Pentofuranosyl-1,3-diazinane-2,4-dione1-beta-D-Arabinofuranosyluracil, Uracil 1-beta-D-arabinofuranoside1-[(2S,5S)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-1,3-DIAZINANE-2,4-DIONE1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]hexahydropyrimidine-2,4-dione
Database identifiers
- CAS
30100-83-5、5627-05-4- PubChem CID
- 321817
- DTXSID
DTXSID10313719
Properties
Computed structural properties
- XLogP
- -2.1
- Topological polar surface area
- 119 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 2
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 335
Physicochemical properties
- Density
- 1.614 · 1.614±0.06 g/cm3(Predicted)
- pka
- 12.4 · 12.40±0.20(Predicted)
Chemistry & industry
Applications
Uses5,6-Dihydro-ara-uridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Suppliers9 total
上海遐瑞医药科技有限公司+86-021-61551413 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
郑州格然林科技有限公司0371-85513397 +86-18610099868 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
浙江天酶生物工程有限公司19967302939 · [email protected]
淄博航宇生物科技发展有限公司+86-0533-2185556 +86-15965530500 · [email protected]
Related reactions
1 records
Compound notes
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