Basic information
- CAS
938-73-8- Standard SMILES
CCOc1ccccc1C(N)=O- InChIKey
SBNKFTQSBPKMBZ-UHFFFAOYSA-N- Molecular formula
- C9H11NO2
- Average molar mass
- 165.19 g/mol
- Monoisotopic mass
- 165.07897859
Overview
2-ethoxybenzamide appears as white or almost-white crystalline powder. Almost odorless. Tasteless. (NTP, 1992)
Names & identifiers
- Preferred name
- 2-Ethoxybenzamide
- IUPAC
- 2-ethoxybenzamide
- English name
- 2-Ethoxybenzamide
- Molecular formula
- C9H11NO2
- Molecular weight
- 165.19
Names & synonyms
2-ETHOXYBENZAMIDEethenzamide938-73-8o-EthoxybenzamideBenzamide, 2-ethoxy-EthbenzamideEtenzamideEthenzamidEthosalicylLucamidePirosolvinaEtamide
Show more names
h.p.209H.P. 209Lindatox
AnovigamEtosalicilEtosalicylKatagrippeProtopyrinTrancalgylEtocilEusal
Database identifiers
- CAS
938-73-8- PubChem CID
- 3282
- DTXSID
DTXSID4020581- ChEMBL
CHEMBL1483877- ChEBI
CHEBI:31564- UNII
- L929ZCK4BF
- EC Number
- 213-346-4
- Nikkaji
- J3.352I
Properties
Computed structural properties
- XLogP
- 1.2
- Topological polar surface area
- 52.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 3
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 159
Experimental & physicochemical properties
LogP1.34
Solubilityless than 1 mg/mL at 61 °F (NTP, 1992)
Melting Point270 to 273 °F (NTP, 1992)
Physical Description2-ethoxybenzamide appears as white or almost-white crystalline powder. Almost odorless. Tasteless. (NTP, 1992)
Physicochemical properties
- Melting point
- 132 · 132-134 °C (lit.)
- Boiling point
- 293.03 °C · 293.03°C (rough estimate)
- Density
- 1.1603 · 1.1603 (rough estimate)
- refractive index
- 1.562 · 1.5620 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Dichloromethane (Slightly)
- form
- Granular Crystalline Powder
- pka
- 15.62 · 15.62±0.50(Predicted)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (24 of 24) of all reports.
Not Classified
Aggregated GHS information provided per 24 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationBenzamide, 2-ethoxy-: Does not have an individual approval but may be used under an appropriate group standard
Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of nitrogen oxides. (NTP, 1992)
Reactive GroupAmides and Imides
Reactivity Profile
2-ETHOXYBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Air and Water ReactionsInsoluble in water.
Hazard Classes and CategoriesNot Classified
Chemistry & industry
Pharmacology
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Uses & manufacturing
General Manufacturing InformationBenzamide, 2-ethoxy-: INACTIVE
Applications
General DescriptionWhite or almost-white crystalline powder. Almost odorless. Tasteless.
Upstream & downstream products
Upstream raw materials
Related reactions
2 records
Compound notes
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