Bis-aminooxy-PEG2
Basic information
- CAS
98627-71-5- Standard SMILES
NOCCOCCOCCON- InChIKey
FDBZGQLBKGNQFT-UHFFFAOYSA-N- Molecular formula
- C6H16N2O4
- Average molar mass
- 180.2 g/mol
- Monoisotopic mass
- 180.11100699
Names & identifiers
- Preferred name
- Bis-aminooxy-PEG2
- IUPAC
- O-[2-[2-(2-aminooxyethoxy)ethoxy]ethyl]hydroxylamine
- English name
- Bis-aminooxy-PEG2
- Molecular formula
- C6H16N2O4
- Molecular weight
- 180.2
Names & synonyms
Bis-aminooxy-PEG298627-71-5Bis-(aminooxy)-peg2MFCD00519242O-[2-[2-(2-aminooxyethoxy)ethoxy]ethyl]hydroxylamineO,O'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(hydroxylamine)SCHEMBL43069O-(2-{2-[2-(aminooxy)ethoxy]ethoxy}ethyl)hydroxylamineDTXSID201176783AminooxyethoxyethoxyethylhydroxylamineAKOS003620562MS-22957
Show more names
1,8-diaminooxy-3,6-dioxaoctaneBis-aminooxy-PEG2 dihydrochlorideO,O′-[1,2-Ethanediylbis(oxy-2,1-ethanediyl)]bis[hydroxylamineHydroxylamine, O,O'-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]bis-
O,O'-[1,2-Ethanediylbis(oxy-2,1-ethanediyl)]bis[hydroxylamine]F82555YDA62771Aminooxy-PEG2-Aminooxyorb1989427CHEMBL12132551,2-bis(2-aminooxyethoxy)ethaneBP-23592
Database identifiers
- CAS
98627-71-5- PubChem CID
- 3306142
- DTXSID
DTXSID201176783- ChEMBL
CHEMBL1213255- Nikkaji
- J3.461.046K
Properties
Computed structural properties
- XLogP
- -1.9
- Topological polar surface area
- 89 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 9
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 73.9
Physicochemical properties
- Boiling point
- 339.7 · 339.7±32.0 °C(Predicted)
- Density
- 1.123 · 1.123±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C, protect from light
- solubility
- Soluble in Water, DMSO, DMF
- pka
- 4.51 · 4.51±0.70(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Chemistry & industry
Applications
DescriptionBis-aminooxy-PEG2 is a homobifunctional PEG linker with two aminooxy groups. The aminooxy group is reactive with aldehyde to form an oxime bond. If a reductant is applied, it will form a hydroxylamine linkage. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
UsesBis-aminooxy-PEG2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
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