Basic information
- CAS
22881-35-2- Standard SMILES
CC(C)c1c(CN(C)C(C)Cc2ccccc2)n(C)n(-c2ccccc2)c1=O- InChIKey
GNUXVOXXWGNPIV-UHFFFAOYSA-N- Molecular formula
- C24H31N3O
- Average molar mass
- 377.5 g/mol
- Monoisotopic mass
- 377.24671262
Overview
1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-yl-3-pyrazolone is a member of pyrazoles and a ring assembly.
Names & identifiers
- Preferred name
- Famprofazone
- IUPAC
- 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
- English name
- FAMPROFAZONE
- Molecular formula
- C24H31N3O
- Molecular weight
- 377.52
Names & synonyms
Famprofazone22881-35-2FamprofazonumFamprofazonaDTXSID3045435HN0NCX453CNSC-759244DTXCID10254351-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-one1-methyl-5-((methyl(1-phenylpropan-2-yl)amino)methyl)-2-phenyl-4-(propan-2-yl)-2,3-dihydro-1H-pyrazol-3-oneRefChem:1399224-isopropyl-2-methyl-3-(N-methyl-N-(alpha-methylphenylethyl)aminomethyl)-1-phenyl-3-pyrazolin-5-one
Show more names
ipyrineo)methyl-component of GewodinFamprofazone 1.0 mg/ml in Methanol4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-antipyrinAntipyrine, 4-isopropyl-3-(alpha-(methyl-(1-phenyl-2-propyl)amino))-3-(n-methyl-(alpha-methyl-beta-phenyl)-ethyl-aminomethyl)-4-isopropyl-norantpyrazolin-5-one,4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamin
245-284-9Famprofazon1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one3H-Pyrazol-3-one, 1,2-dihydro-1-methyl-4-(1-methylethyl)-5-[[methyl(1-methyl-2-phenylethyl)amino]methyl]-2-phenyl-Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)methylamino)methyl-4-isopropyl-1-methyl-5-((methyl(1-phenylpropan-2-yl)amino)methyl)-2-phenyl-1,2-dihydro-3H-pyrazol-3-oneGeodowinFamprofazone [INN:BAN]
Properties
Computed structural properties
- XLogP
- 5
- Topological polar surface area
- 26.8 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 7
- Heavy atoms
- 28
- Formal charge
- 0
- Complexity
- 558
Experimental & physicochemical properties
Human DrugsPharmaceuticals
Collision Cross Section
189.99 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
190.9 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- Melting point
- 132 · 132-133 °C(Solv: ethanol (64-17-5))
- Boiling point
- 485.1 · 485.1±55.0 °C(Predicted)
- Density
- 1.083 · 1.083±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
- form
- Solid
- pka
- 10.28 · 10.28±0.50(Predicted)
- color
- White to Off-White
- EWG's Food Scores
- 1 · 1
- FDA UNII
- 0 NCX453C · HN0NCX453C
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- wgk
- 3
- rtecs
- UQ9451000
- Toxicity
- mouse,LD50,oral,2gm/kg (2000mg/kg),Schweizerische Medizinische Wochenschrift. Vol. 84, Pg. 351, 1954.
- risk_code
- 22
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn
- safety_code
- 36
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
Cellular LocationsMembrane
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
Usesanalgesic, antipyretic, CNS stimulant
UsesFamprofazone, which is known to metabolize to Methamphetamine (M258795) and Amphetamine (A634248) and is included in the prohibited list of the World Anti-Doping Agency. Controlled substance (stimulant).
Suppliers19 total
艾吉析科技（上海）有限公司17717235263 · [email protected]
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
Nantong HI-FUTURE Biology Co., Ltd.+86-18051384581 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
天津普西唐生物医药科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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