Basic information
- CAS
7729-20-6- Standard SMILES
NC(CSSCC(N)C(=O)NCC(=O)O)C(=O)NCC(=O)O- InChIKey
KDJVKDYFFTWHBO-UHFFFAOYSA-N- Molecular formula
- C10H18N4O6S2
- Average molar mass
- 354.4 g/mol
- Monoisotopic mass
- 354.06677665
Overview
Cys-Gly disulfide is an organic disulfide obtained by the oxidation of two Cys-Gly molecules which are then linked via a disulfide bond. It is an organic disulfide and a dipeptide. It is functionally related to a cystine. It is a tautomer of a Cys-Gly disulfide dizwitterion.
Names & identifiers
- Preferred name
- ((2-Amino-3-((2-amino-3-((carboxymethyl)amino)-3-oxopropyl)dithio)propanoyl)amino)acetic acid
- IUPAC
- 2-[[2-amino-3-[[2-amino-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]propanoyl]amino]acetic acid
- English name
- (H-Cys-Gly-OH)2
- Molecular formula
- C10H18N4O6S2
- Molecular weight
- 354.4
Names & synonyms
7729-20-6((2-Amino-3-((2-amino-3-((carboxymethyl)amino)-3-oxopropyl)dithio)propanoyl)amino)acetic acidNSC333711(H-Cys-Gly-OH)2 (Disulfide bond)NSC 3337112-[[2-amino-3-[[2-amino-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]propanoyl]amino]acetic acid(H-Cys-Gly-OH)2Cys-Gly, oxidisedCys(Cys-Gly)-GlyCys-Gly dimerCys-Gly disulfide(Cys-Gly)2
Show more names
1')-disulfideCYS[CYS-GLY]-GLYCys-Gly, oxidizedCystinyl-bis-glycineN,N'-L-CystyldiglycineL-CYSTINYL-BIS-GLYCINEOxidized cysteinylglycine
SCHEMBL14789149CHEBI:133040NSC-333711DA-52262FC1080172,2'-{disulfanediylbis[(2-amino-1-oxopropane-3,1-diyl)azanediyl]}diacetic acid2-[[2-amino-3-[[2-amino-3-(carboxymethylamino)-3-keto-propyl]disulfanyl]propanoyl]amino]acetic acid2-[[2-amino-3-[[2-amino-3-(carboxymethylamino)-3-oxo-propyl]disulfanyl]propanoyl]amino]acetic acid
Properties
Computed structural properties
- XLogP
- -7.6
- Topological polar surface area
- 235 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 11
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 384
Physicochemical properties
- Boiling point
- 788.5 · 788.5±60.0 °C(Predicted)
- Density
- 1.535 · 1.535±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- solubility
- PBS (pH 7.2): 1 mg/ml
- form
- A crystalline solid
- pka
- 2.72 · 2.72±0.10(Predicted)
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Applications
DescriptionCystinyl-bis-glycine is a dipeptide intermediate in the synthesis of oxidized glutathione that is composed of two cysteinylglycine peptides linked by a disulfide bond. It is formed via nonenzymatic oxidation of cysteinylglycine, a glutathione catabolite produced by γ-glutamyl transpeptidase.
Suppliers30 total
Aladdin Scientific[email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
NANJING YINGWEN BIOTECHNOLOGY CO LTD+8613382787392 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
康明永瑞生物科技（苏州）有限公司17751201929; 17751201929 · [email protected]
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
上海阿拉丁生化科技股份有限公司6206333 13167063860 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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