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N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide

HCID 3344037
NotesReactions

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Basic information

CAS
143503-03-1
Standard SMILES
COc1cc2c(cc1OC)C(=O)N(c1ccc(N3C(=O)C=CC3=O)cc1)C2
InChIKey
ISCHQGBNSNVWCQ-UHFFFAOYSA-N
Molecular formula
C20H16N2O5
Average molar mass
364.357 g/mol
Monoisotopic mass
364.10592161

Names & identifiers

Preferred name
N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide
IUPAC
1-[4-(5,6-Dimethoxy-1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]-1H-pyrrole-2,5-dione
English name
N-(4-(5 6-Dimethoxy-N-phthalimidinyl)
Molecular formula
C20H16N2O5
Molecular weight
364.35

Names & synonyms

N-(4-(5 6-Dimethoxy-N-phthalimidinyl)1-[4-(5,6-dimethoxy-3-oxo-1H-isoindol-2-yl)phenyl]pyrrole-2,5-dione1H-Pyrrole-2,5-dione, 1-[4-(1,3-dihydro-5,6-dimethoxy-1-oxo-2H-isoindol-2-yl)phenyl]-

Database identifiers

CAS
143503-03-1
PubChem CID
3344037
DTXSID
DTXSID20391644

Properties

Physicochemical properties

Boiling point
607.6 · 607.6±55.0 °C(Predicted)
Density
1.406 · 1.406±0.06 g/cm3(Predicted)
pka
-0.4 · -0.40±0.20(Predicted)
WGK Germany
3 · 3

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

Safety data

wgk
3

Chemistry & industry

Applications · 2 items

UsesNonfluorescent N-substituted maleimides react selectively with thiol compounds to form fluorescent derivatives. Fluorescent intensity of the dimethoxyphthalimidyl group is higher than that of the nonsubsituted phthalimidyl group.

UsesN-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide is a thiol-reactive compound. N-[4-(5,6-Dimethoxy-N-phthalimidinyl)phenyl]maleimide selectively reacts with thiols. It can be used as a pre-column labeling reagent in HPLC and in the determination of thiols in biological fluids.

Suppliers3 total

北京阿克曼科技有限公司18001219251 · [email protected]
安耐吉化学&3A(安徽泽升科技有限公司)021-58432009 400-005-6266 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]

Related reactions

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Compound notes

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