Basic information
- CAS
2746-81-8- Standard SMILES
CCCCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1- InChIKey
LRWSFOSWNAQHHW-UHFFFAOYSA-N- Molecular formula
- C29H38F3N3O2S
- Average molar mass
- 549.7 g/mol
- Monoisotopic mass
- 549.26368312
Overview
Fluphenazine enanthate is a member of phenothiazines.
Names & identifiers
- Preferred name
- Fluphenazine Enanthate
- IUPAC
- 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate
- English name
- fluphenazine O-enantate
- Molecular formula
- C29H38F3N3O2S
- Molecular weight
- 549.698
Names & synonyms
fluphenazine enanthate2746-81-8Prolixin EnanthateFluphenazine enantateFlufenanSQ 16,114QSB34YF0W9Fluphenazini enantasDTXSID6023070SQ 161442-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl heptanoate2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl heptanoate
Show more names
fluphenazine O-enantateFluphenazine enantate CRSFLUPHENAZINE ENANTHATE (LIQ)Fluphenazine Decanoate Impurity 3 (Fluphenazine Decanoate EP Impurity C)2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl heptanoateenanthic acid 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl esterHeptanoic acid, 2-4-3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl-1-piperazinylethyl ester
2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl heptanoateModiten enant2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl heptanoateRefChem:55216DTXCID403070EutimoxModiten enanthateModiten-retard
Database identifiers
- CAS
2746-81-8- PubChem CID
- 3389
- DTXSID
DTXSID6023070- ChEMBL
CHEMBL1200951- ChEBI
CHEBI:5125- UNII
- QSB34YF0W9
- EC Number
- 220-385-0
- Nikkaji
- J7.903K
Properties
Computed structural properties
- XLogP
- 7.4
- Topological polar surface area
- 61.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 13
- Heavy atoms
- 38
- Formal charge
- 0
- Complexity
- 720
Experimental & physicochemical properties
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physicochemical properties
- Melting point
- 184.5 °C · 184.5°C
- Boiling point
- 629.4 · 629.4±55.0 °C(Predicted)
- Density
- 1.1661 · 1.1661 (estimate)
- storage temp.
- 2 · 2-8°C
- solubility
- Practically insoluble in water, very soluble in ethanol and in methylene chloride, freely soluble in methanol.
- pka
- 7.32 · 7.32±0.10(Predicted)
- Major Application
- pharmaceutical (small molecule)
- InChIKey
- LRWSFOSWNAQHHW-UHFFFAOYSA-N
- SMILES
- FC(F)(F)c1cc2c(cc1)Sc3c(cccc3)N2CCCN4CCN(CC4)CCOC(=O)CCCCCC
- FDA UNII
- 34 YF0W9 · QSB34YF0W9
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 6 · GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- 301 · H301-H360
- Precautionary statements
- 201 · P201-P301+P310+P330
- RIDADR
- 3249 · 3249
- WGK Germany
- 3 · WGK 3
- HazardClass
- 6.1 · 6.1(b)
- PackingGroup
- III
- Storage Class
- 6.1 C · 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- Hazard Classifications
- 3 OralRepr · Acute Tox. 3 OralRepr. 1A
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P233, P260, P261, P264, P270, P271, P272, P280, P284, P301+P317, P302+P352, P304+P340, P317, P321, P330, P333+P317, P342+P316, P362+P364, P403, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 17 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
Hazard Traits - Bioaccumulation; Environmental Persistence
Heptanoic acid, 2-4-3-2-(trifluoromethyl)-10H-phenothiazin-10-ylpropyl-1-piperazinylethyl ester: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Heptanoic acid, 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester: Environment tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- wgk
- WGK 3
- ridadr
- 3249
- Signal word
- Danger
- Symbol(GHS)
- GHS06,GHS08
- hazard_class
- 6.1(b)
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- packing_group
- III
- Hazard statements
- H301-H360
- Hazard Classifications
- Acute Tox. 3 OralRepr. 1A
- Precautionary statements
- P201-P301+P310+P330
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Applications
UsesFluphenazine Enanthate serves as a medication for the treatment of tardive dyskinesia (TD) in monkeys. Fluphenazine Enanthate also functions as a medication for the antipsychotics study on human prolactin levels. Fluphenazine Enanthate reduces the blood pressure of pentobarbital Na anesthetized dogs, reduces heart rate in anesthetized dogs, and increases coronary blood flow and femoral blood flow in anesthetized dogs enhancing cardiovascular functions.
UsesAntipsychotic.
Suppliers18 total
孟成科技（上海）有限公司400-820-6829 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
青岛海智微元生物科技有限公司18317699790 18317699790 · [email protected]
TLC梯尔希（南京）药物研发有限公司18012923235 · [email protected]
珠海安哲生物科技有限公司13169972583 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
BOC Sciences16314854226 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
上海立崎生物医学研究中心18014399201 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354 · [email protected]
湖北清北云研医药科技有限责任公司18162595016; 18162595016 · [email protected]
Additional notes
DefinitionChEBI: Fluphenazine enanthate is a member of phenothiazines.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…