Basic information
- CAS
17598-94-6- Standard SMILES
CCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCC- InChIKey
OQQOAWVKVDAJOI-UHFFFAOYSA-N- Molecular formula
- C27H52O5
- Average molar mass
- 456.7 g/mol
- Monoisotopic mass
- 456.38147475
Overview
The Expert Panel concluded that ... Glyceryl Dilaurate is safe as cosmetic ingredients in the practices of use and concentrations as described in this safety assessment provided that the content of 1,2-diesters is not high enough to induce epidermal hyperplasia.
Names & identifiers
- Preferred name
- 1,2-Dilaurin
- IUPAC
- (2-dodecanoyloxy-3-hydroxypropyl) dodecanoate
- English name
- 1,2-Dilaurin
- Molecular formula
- C27H52O5
- Molecular weight
- 456.7
Names & synonyms
1,2-Dilaurin17598-94-6Glyceryl 1,2-dilaurate1,2-Didodecanoylglycerolrac-1,2-DidodecanoylglycerolDodecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester9S1016G3A2DTXSID30880897glyceryl-dilaurateRefChem:663523DTXCID301022242racemic mixture of 1,2-didodecanoylglycerol
Show more names
DiglycerideDIDODECANOINDILAURIN (C12:0)1,3-dilaurate glycerol
1,2-Dilauroyl-sn-glycerolDilaurinGLYCERYL DILAURATED-alpha,beta-Dilaurin(2-dodecanoyloxy-3-hydroxypropyl) dodecanoate3-Hydroxypropane-1,2-diyl didodecanoateUNII-9S1016G3A21,2-dilauroylglycerol
Database identifiers
- CAS
17598-94-6、27638-00-2- PubChem CID
- 33979
- DTXSID
DTXSID30880897- UNII
- 9S1016G3A2
- EC Number
- 248-586-9
- Nikkaji
- J13.607G
Properties
Computed structural properties
- XLogP
- 9.7
- Topological polar surface area
- 72.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 26
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 424
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Glyceryl Dilaurate) -> CIR (Cosmetic Ingredient Review)
Emollient; Emulsifying
Physicochemical properties
- Melting point
- 53 · 53-56 °C
- Boiling point
- 531 · 531.0±17.0 °C(Predicted)
- Density
- 0.953 · 0.953±0.06 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- pka
- 13.69 · 13.69±0.10(Predicted)
- form
- A crystalline solid
- color
- White to off-white
- FDA UNII
- 9 S1016G3A2 · 9S1016G3A2
- WGK Germany
- 1 · 1
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 100% (150 of 150) of all reports.
Not Classified
Aggregated GHS information provided per 150 reports by companies from 1 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesNot Classified
Toxicology
Toxicity Summary
The Expert Panel concluded that ... Glyceryl Dilaurate is safe as cosmetic ingredients in the practices of use and concentrations as described in this safety assessment provided that the content of 1,2-diesters is not high enough to induce epidermal hyperplasia.
Safe for use in cosmetics, with qualifications
Safety data
- wgk
- 1
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Glyceryl Dilaurate
Household ProductsInformation on 23 consumer products that contain Glyceryl dilaurate in the following categories is provided:
Use ClassificationCosmetics -> Emollient; Emulsifying
Applications
Uses1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).
Suppliers37 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
陕西帕尼尔生物科技有限公司029-84385017; +8613259417953 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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