Safrazine
Basic information
- CAS
33419-68-0- Standard SMILES
CC(CCc1ccc2c(c1)OCO2)NN- InChIKey
IBWPUTAKVGZXRB-UHFFFAOYSA-N- Molecular formula
- C11H16N2O2
- Average molar mass
- 208.26 g/mol
- Monoisotopic mass
- 208.12117776
Overview
Safrazine is a member of the hydrazine family with non-selective and irreversible inhibitor effects against monoamine oxidases. In 1960, it was used as an antidepressant but it is now discontinued.
Names & identifiers
- Preferred name
- Safrazine
- IUPAC
- 4-(1,3-benzodioxol-5-yl)butan-2-ylhydrazine
- English name
- Safrazine
- Molecular formula
- C11H16N2O2
- Molecular weight
- 208.25694
Names & synonyms
SafrazineSaphrazine33419-68-0F5G0P5378C[4-(2H-1,3-BENZODIOXOL-5-YL)BUTAN-2-YL]HYDRAZINEDTXSID60860006(4-(2H-1,3-benzodioxol-5-yl)butan-2-yl)hydrazinebeta-piperonylisopropylhydrazineRefChem:180824DTXCID10197298858830-96-3(4-(Benzo[d][1,3]dioxol-5-yl)butan-2-yl)hydrazine
Show more names
Safrasine1-[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]hydrazine
Hydrazine, (1-methyl-3-(3,4-(methylenedioxy)phenyl)propyl)-4-(1,3-benzodioxol-5-yl)butan-2-ylhydrazine[4-(1,3-dioxaindan-5-yl)butan-2-yl]hydrazineSafrasin1-[4-(2H-1,3-benzodioxol-5-yl)butan-2-yl]hydrazineNCGC00183002-01BRN 1376116Safra
Database identifiers
- CAS
33419-68-0- PubChem CID
- 34042
- DTXSID
DTXSID60860006- ChEMBL
CHEMBL3301845- UNII
- F5G0P5378C
- Nikkaji
- J77.804D
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 56.5 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 201
Physicochemical properties
- Boiling point
- 347.46 °C · 347.46°C (rough estimate)
- Density
- 1.1123 · 1.1123 (rough estimate)
- refractive index
- 1.5 · 1.5000 (estimate)
- FDA UNII
- 5 G0P5378C · F5G0P5378C
Chemistry & industry
Applications
UsesSafrazine is an irreversible, non-specific and orally active monoamine oxidase (MAO) inhibitor. Safrazine can be used for the research of depression[1].
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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