Basic information
- CAS
24243-97-8- Standard SMILES
Cc1ccc(C(C)C)c(OCC2=NCCN2)c1- InChIKey
QRORCRWSRPKEHR-UHFFFAOYSA-N- Molecular formula
- C14H20N2O
- Average molar mass
- 232.32 g/mol
- Monoisotopic mass
- 232.15756327
Overview
Tymazoline is a monoterpenoid.
Names & identifiers
- Preferred name
- Tymazoline
- IUPAC
- 2-[(5-methyl-2-propan-2-ylphenoxy)methyl]-4,5-dihydro-1H-imidazole
- English name
- TYMAZOLINE
- Molecular formula
- C14H20N2O
- Molecular weight
- 232.32
Names & synonyms
Tymazoline24243-97-8PernazeneTymazolinTymazoline [BAN]Tymazoline (BAN)2-(Thymyloxymethyl)glyoxalidineUNII-U993RH5585TYMAZOLINE [MI]U993RH5585TYMAZOLINE [WHO-DD]2-Imidazoline, 2-((thymyloxy)methyl)-
Show more names
4,5-Dihydro-2-[(5-methyl-2-isopropylphenoxy)methyl]-1H-imidazole1H-Imidazole, 4,5-dihydro-2-[[5-methyl-2-(1-methylethyl)phenoxy]methyl]-
DTXSID401789392-(2-Isopropyl-5-methylphenoxymethyl)-2-imidazoline1,4,5-Dihydro-2-(2-isopropyl-5-methylphenoxymethyl)imidazolPernazene (TN)2-[5-methyl-2-(propan-2-yl)phenoxymethyl]-4,5-dihydro-1H-imidazole1H-Imidazole, 4,5-dihydro-2-((5-methyl-2-(1-methylethyl)phenoxy)methyl)-2-(5-methyl-2-(propan-2-yl)phenoxymethyl)-4,5-dihydro-1H-imidazoleRefChem:192635
Database identifiers
- CAS
24243-97-8- PubChem CID
- 34154
- DTXSID
DTXSID40178939- ChEMBL
CHEMBL2106467- ChEBI
CHEBI:134947- UNII
Properties
Computed structural properties
- XLogP
- 2.4
- Topological polar surface area
- 33.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 4
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 275
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Physical DescriptionSolid
Physicochemical properties
- FDA UNII
- 993 RH5585 · U993RH5585
- ATC code
- 1 AA13 · R01AA13
Chemistry & industry
Pharmacology
ATC Code
R - Respiratory system
QR - Respiratory system
PharmacodynamicsTymazoline is a drug with antihistaminic and sympathomimetic properties. It locally reduces swelling, inflammation and mucosal secretions of the nasal passages.
Mechanism of Action
Thymazen causes vasoconstriction of the nasal mucosa, reducing congestion and thus the swelling of the mucosa. Also reduces the secretions from the nose. Thymazen acts on alpha-adrenergic receptors, which reduces local inflammation of the nasal mucosa especially if their cause is an allergy.
Cellular LocationsExtracellular
Suppliers5 total
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
Shanxi Tihondan Pharmaceutical Technology Co., Ltd+8618235132063 · [email protected]
苏州美诺医药科技有限公司0512-69561983 13914027025 · [email protected]
青岛浩海安杰医药科技有限公司156-6622-8711 18639325623 · [email protected]
Additional notes
DefinitionChEBI: Tymazoline is a monoterpenoid.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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