Basic information
- CAS
24932-48-7- Standard SMILES
Cc1cc(Br)c(Br)cc1C- InChIKey
BCIDDURGCAHERU-UHFFFAOYSA-N- Molecular formula
- C8H8Br2
- Average molar mass
- 263.96 g/mol
- Monoisotopic mass
- 261.89928
Names & identifiers
- Preferred name
- Benzene, 1,2-dibromo-4,5-dimethyl-
- IUPAC
- 1,2-dibromo-4,5-dimethylbenzene
- English name
- 4,5-Dibromo-o-xylene
- Molecular formula
- C8H8Br2
- Molecular weight
- 263.96
Names & synonyms
1,2-Dibromo-4,5-dimethylbenzene24932-48-7Benzene, 1,2-dibromo-4,5-dimethyl-DTXSID00179644RefChem:562248DTXCID60102135626-299-3InChI=1/C8H8Br2/c1-5-3-7(9)8(10)4-6(5)2/h3-4H,1-2H4,5-Dibromo-o-xyleneMFCD00082743SCHEMBL11355941,2-Dibromo-4,5-dimethylbenzene, 97%
Show more names
4,5-Dibromo-2-methyl-toluene2-Dibromo-4,5-dimethylbenzene1,2-DiMethyl-4,5-dibroMobenzene4,5-DIBROMO-1,2-DIMETHYLBENZENE1,2-Dibromo-4,5-dimethylbenzene >1,2-Dibromo-4,5-dimethylbenzene 98+%4,5-DIBROMO-O-XYLENE ISO 9001：2015 REACH
1,2-DIBROMO-4,5-DIMETHYL-BENZENE4,5-Dibromo-1,2-xylene; 4,5-Dibromo-o-xylene4,5-dibromo-ortho-xyleneBenzene, 1,2-dibromo-4,SCHEMBL29637482BBL100890SBB054194TD1273
Database identifiers
- CAS
24932-48-7- PubChem CID
- 34347
- DTXSID
DTXSID00179644- EC Number
- 626-299-3
- Nikkaji
- J88.307G
Properties
Computed structural properties
- XLogP
- 4
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 0
- Heavy atoms
- 10
- Formal charge
- 0
- Complexity
- 99.8
Physicochemical properties
- Melting point
- 85 · 85-89 °C (lit.)
- Boiling point
- 278 °C · 278 °C
- Density
- 1.7485 · 1.7485 (rough estimate)
- refractive index
- 1.6146 · 1.6146 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Pale Yellow
- BRN
- 2206183 · 2206183
- InChI
- InChI=1S/C8H8Br2/c1-5-3-7(9)8(10)4-6(5)2/h3-4H,1-2H3
- InChIKey
- BCIDDURGCAHERU-UHFFFAOYSA-N
- SMILES
- C1(Br)=CC(C)=C(C)C=C1Br
- CAS DataBase Reference
- 24932 · 24932-48-7(CAS DataBase Reference)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- hs_code
- 29039990
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36/37
- hazard_class
- IRRITANT
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335-H413
- Hazard Classifications
- Aquatic Chronic 4Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P273-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses1,2-Dibromo-4,5-dimethylbenzene is used as a reagent in the synthesis of Thalidomide (T338850); an inhibitor of FGF-induced angiogenesis and replication of human immunodeficiency virus type 1. Also a teratogenic sedative and immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
Uses1,2-Dibromo-4,5-dimethylbenzene can be used in the synthesis of alkylamino zinc(II)phthalocyanines, with potential application as photosensitizers in photodynamic therapy. It can also be used in the synthesis of 1,2-dibromo-4,5-bis(dibromomethyl)benzene via reaction with azobisisobutyronitrile.
General Description1,2-Dibromo-4,5-dimethylbenzene can be synthesized via bromination of o-xylene.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
湖北蝶化新材料科技有限公司86-18372897-544 18995560451 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
上海炎泽化工有限公司
Related reactions
4 records
Compound notes
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