Basic information
- CAS
477-82-7- Standard SMILES
COc1c2c(cc3c1c(=O)c1ccccc1n3C)OCO2- InChIKey
ULBVHYNIDQSMFC-UHFFFAOYSA-N- Molecular formula
- C16H13NO4
- Average molar mass
- 283.28 g/mol
- Monoisotopic mass
- 283.0844579
Overview
EVOXANTHINE has been reported in Balfourodendron riedelianum, Vepris suaveolens, and Ruta graveolens with data available.
Names & identifiers
- Preferred name
- 11-Methoxy-5-methyl-1,3-dioxolo(4,5-b)acridin-10(5H)-one
- IUPAC
- 11-methoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-one
- English name
- 11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one
- Molecular formula
- C16H13NO4
- Molecular weight
- 283.28
Names & synonyms
EVOXANTHINE477-82-711-methoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10-oneDTXSID0032483911-methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one11-methoxy-5-methyl-(1,3)dioxolo(4,5-b)acridin-10-one11-Methoxy-5-methyl-1,3-dioxolo(4,5-b)acridin-10(5H)-oneRefChem:1057369DTXCID8027595611-Methoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10(5H)-oneNSC407812MLS003373786
Show more names
1,3-Dioxolo[4,5-b]acridin-10(5H)-one, 11-methoxy-5-methyl-Evoxanthinorb1694353ULBVHYNIDQSMFC-UHFFFAOYSA-NHY-N8364MFCD2991870011-METHOXY-5-METHYL-2H,5H,10H-[1,3]DIOXOLO[4,5-B]ACRIDIN-10-ONEAKOS027323264
Database identifiers
- CAS
477-82-7- PubChem CID
- 348484
- DTXSID
DTXSID00324839- Nikkaji
- J12.553I
Properties
Computed structural properties
- XLogP
- 2.9
- Topological polar surface area
- 48 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 1
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 429
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- form
- A solid
Chemistry & industry
Applications
DescriptionEvoxanthine is an alkaloid that has been found in O. renieri and has antimalarial and anticancer activities. It is active against P. falciparum with an IC50 value of 67.6 μg/ml. Evoxanthine decreases proliferation of nine sensitive and drug-resistant cancer cell lines (IC50s = 6.11-80.99 μM).
UsesEvoxanthine is a compound that can be isolated from the stem bark of Pleiocarpa pycnantha[1].
Suppliers12 total
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
Aladdin Scientific[email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
北京百奥创新科技有限公司15522676233 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
上海贝万塔生物科技有限公司021-67187366 19901745723 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 17389186172 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海一飞生物科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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