Pifoxime
Basic information
- CAS
31224-92-7- Standard SMILES
CC(=NO)c1ccc(OCC(=O)N2CCCCC2)cc1- InChIKey
XUDSQIDNHJMBBW-UHFFFAOYSA-N- Molecular formula
- C15H20N2O3
- Average molar mass
- 276.33 g/mol
- Monoisotopic mass
- 276.1473925
Names & identifiers
- Preferred name
- Pifoxime
- IUPAC
- 2-[4-(N-hydroxy-C-methylcarbonimidoyl)phenoxy]-1-piperidin-1-ylethanone
- English name
- Pifoxime
- Molecular formula
- C15H20N2O3
- Molecular weight
- 276.33
Names & synonyms
PifoximaPifoxime [INN]FlamanilPifoximumPixifenide31224-92-7Pifoximum [INN-Latin]Pifoxima [INN-Spanish]UNII-5947ECZ7WH5947ECZ7WHSW 771-((p-Acetylphenoxy)acetyl)piperidine p-oxime
Show more names
SW-77LF-77Pifoxime1-[[4-[1-(Hydroxyimino)ethyl]phenoxy]acetyl]piperidineEthanone, 2-[4-[1-(hydroxyimino)ethyl]phenoxy]-1-(1-piperidinyl)-
BRN 12917311-(p-(1-Oximidoethyl)phenoxyacetyl)piperidineN-(p-(1-Isonitrosoethyl)phenoxyacetyl)piperidine4'-(1-Piperidylcarbonylmethoxy)acetophenone oxime5-20-03-00037 (Beilstein Handbook Reference)1-((4-(1-Hydroxyimino)ethyl)phenoxyacetyl)piperidinePifoximum (INN-Latin)Pifoxima (INN-Spanish)
Database identifiers
- CAS
31224-92-7- PubChem CID
- 35755
- ChEMBL
CHEMBL1998966- UNII
- 5947ECZ7WH
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 62.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 343
Physicochemical properties
- Boiling point
- 494.7 · 494.7±30.0 °C(Predicted)
- Density
- 1.18 · 1.18±0.1 g/cm3(Predicted)
- pka
- 11.5 · 11.50±0.70(Predicted)
- FDA UNII
- 5947 ECZ7WH · 5947ECZ7WH
Chemistry & industry
Applications
UsesPifoxime is a COX-1/2 inhibitor, a non-steroidal anti-inflammatory agent (NSAID). Pifoxime shows anti-inflammatory activity, and can be used in neuropsychiatric research[1][2].
Upstream & downstream products
Upstream raw materials
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Compound notes
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