Basic information
- CAS
60-26-4- Standard SMILES
C[N+](C)(C)CCCCCC[N+](C)(C)C- InChIKey
VZJFGSRCJCXDSG-UHFFFAOYSA-N- Molecular formula
- C12H30N2+2
- Average molar mass
- 202.38 g/mol
- Monoisotopic mass
- 202.24089897
Overview
Hexamethonium is a quaternary ammonium salt.
Names & identifiers
- Preferred name
- Hexamethonium
- IUPAC
- trimethyl-[6-(trimethylazaniumyl)hexyl]azanium
- English name
- HEXAMETHONIUM CHLORIDE
- Molecular formula
- C12H30N2+2
- Molecular weight
- 202.38
Names & synonyms
hexamethoniumHexaniumHexonium60-26-4hexamethonehexathonideHexamethonumHexamethonium ionHexamethonium cation1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-3C9PSP36Z2Hexane-1,6-bis(trimethylammonium)
Show more names
bistriumesametoniobenzohexamethoniumHexamethonium Free Basehexamethylenebis(trimethyl-ammoniuHexamethylenebis[trimethylaminium]
Bitartrate, HexamethoniumAmmonium, hexamethylenebis(trimethyl-trimethyl[6-(trimethylazaniumyl)hexyl]azaniumtrimethyl(6-(trimethylazaniumyl)hexyl)azaniumtrimethyl-(6-(trimethylammonio)hexyl)ammoniumtrimethyl-[6-(trimethylammonio)hexyl]ammoniumIodide, HexamethoniumDiiodide, Hexamethonium
Database identifiers
- CAS
60-26-4- PubChem CID
- 3604
- DTXSID
DTXSID9045053- ChEMBL
CHEMBL100622- ChEBI
CHEBI:5700
Properties
Computed structural properties
- XLogP
- 1.8
- Topological polar surface area
- 0 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 7
- Heavy atoms
- 14
- Formal charge
- 2
- Complexity
- 121
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Melting Point290-291
Physicochemical properties
- FDA UNII
- 3 C9PSP36Z2 · 3C9PSP36Z2
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
Upstream & downstream products
Upstream raw materials
Suppliers3 total
金瓯生物医药（南京）有限公司13000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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