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Ethidium

HCID 3624
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Basic informationOverviewNames & identifiersPropertiesChemistry & industryRelated reactionsCompound notes
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Basic information

CAS
3546-21-2
Standard SMILES
CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21
InChIKey
QTANTQQOYSUMLC-UHFFFAOYSA-O
Molecular formula
C21H20N3+
Average molar mass
314.4 g/mol
Monoisotopic mass
314.16572265

Overview

Ethidium is the fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA. It has a role as an intercalator and a fluorochrome. It derives from a hydride of a phenanthridine.

Names & identifiers

Preferred name
Ethidium
IUPAC
5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine
English name
Ethidium
Molecular formula
C21H20N3+
Molecular weight
314.41

Names & synonyms

EthidiumhomidiumEthidium cation3546-21-2BabidiumHomidium cationHomidium ion3,8-Diamino-5-ethyl-6-phenylphenanthridiniumEN464416SIPhenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-RD-1572DTXSID9048487
Show more names
Homidium Free BasePHENANTHRIDINIUM,3,8-DIAMINO-5-ETHYL-6-PHENYL-ethidium, Dromilac, 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium cation, ethidium bromide, ethidium cation, ethidium ion, ethidium
CHEBI:424782,7-diamino-9-phenyl-10-ethylphenanthridinium3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium2,7-DIAMINO-10-ETHYL-9-PHENYLPHENANTHRIDINIUMRefChem:921221DTXCID9028461Novidium5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine

Database identifiers

CAS
3546-21-2
PubChem CID
3624
DTXSID
DTXSID9048487
ChEMBL
CHEMBL48166
ChEBI
CHEBI:42478
UNII

Properties

Computed structural properties

XLogP
4.2
Topological polar surface area
55.9 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
2
Rotatable bonds
2
Heavy atoms
24
Formal charge
1
Complexity
419

Experimental & physicochemical properties

Collision Cross Section172.71 Ų [M]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Physicochemical properties

FDA UNII
464416 SI · EN464416SI

Chemistry & industry

Pharmacology

ATC CodeQP - Antiparasitic products, insecticides and repellents
MeSH Pharmacological Classification · 5 items

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.

Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.

Suppliers5 total

Syntechem Co.,Ltd[email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
河南威梯希化工科技有限公司0371-63284658 18135795563 · [email protected]
乐山阿普莱化学科技有限公司18011665355 · [email protected]

Related reactions

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Compound notes

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On this pageBasic informationOverviewNames & identifiersPropertiesChemistry & industryRelated reactionsCompound notes
EN464416SI
Nikkaji
J5.164K
TargetMol中国(陶术生物)15002134094 · [email protected]

Additional notes

DefinitionChEBI: The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.