Completing data — usually done within a minute
Basic information
- CAS
121445-24-7- Standard SMILES
Nc1c2c(nc3ccccc13)CCCC2O- InChIKey
HLVVITIHAZBPKB-UHFFFAOYSA-N- Molecular formula
- C13H14N2O
- Average molar mass
- 214.268 g/mol
- Monoisotopic mass
- 214.11061307
Names & identifiers
- Preferred name
- Velnacrine
- IUPAC
- 9-Amino-1,2,3,4-tetrahydroacridin-1-ol
- English name
- 9-Amino-1,2,3,4-tetrahydro-acridin-1-ol
- Molecular formula
- C13H14N2O
- Molecular weight
- 214.26
Names & synonyms
PD-1316201-Hydroxytacrine9-Amino-1,2,3,4-tetrahydro-acridin-1-ol
Database identifiers
- CAS
121445-24-7、121445-26-9、124027-47-0- PubChem CID
- 3655
- DTXSID
DTXSID4046945- ChEMBL
CHEMBL51934- ChEBI
CHEBI:91990- UNII
- JFN3Z63E2C、OQL6V4U301、Y2P6NV151K
- Nikkaji
- J344.576C
Properties
Physicochemical properties
- Melting point
- 245 ℃ · 245℃
- Boiling point
- 450.3 · 450.3±45.0 °C(Predicted)
- Density
- 1.315 · 1.315±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 13.47 · 13.47±0.20(Predicted)
- FDA UNII
- 2 P6NV151K · Y2P6NV151K
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
UsesVelnacrine (HP 029 free base) is an inhibitor for acetylcholinesterase (AChE), with an IC50 of 3.27 μM. Velnacrine reverses the Scopolamine (HY-N0296)-induced amnesia in rat models, and exhibits acute toxicity with LD50 of 65 mg/kg[1].
Suppliers19 total
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
United Life Science020-82099279 18988941402 · [email protected]
TargetMol 中国（陶术生物）400-821-0310 15002144251 · [email protected]
南京友杰医药科技有限公司18860950986 · [email protected]
上海肯恩化学科技有限公司13120367189;18621755571 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
BOC Sciences16314854226 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
苏州莱惠生物技术有限公司
Related reactions
32 records
Compound notes
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