CAS 34346-01-5 Hydroxyacetic acid--2-hydroxypropanoic acid (1/1) (HCID 36797)

Names & identifiers

Preferred name: Hydroxyacetic acid--2-hydroxypropanoic acid (1/1)
IUPAC: 2-hydroxyacetic acid;2-hydroxypropanoic acid
English name: Propanoic acid, 2-?hydroxy-?, polymer with 2-?hydroxyacetic acid
Molecular formula: C5H10O6
Molecular weight: 166.13

Names & synonyms

RefChem:1087049153439-97-5DTXSID00934750DTXCID001363392Hydroxyacetic acid--2-hydroxypropanoic acid (1/1)PLGA34346-01-52-hydroxyacetic acid;2-hydroxypropanoic acidPLGA 7520glycolic acid lactic acidlactic acid glycolic acidDL-lactic acid glycolic acid

Show more names

Polyglactin 910POLY(D-LACTIDE)POLY(DL-LACTIDE)PLGA polymerLACTEL BP-0500PURASORB(R) PDPURASORB(R) PDLD-LACTIDE POLYMERPoly(glycolide-lactide)Poly(DL-lactic acid-glycolic acid)

SCHEMBL41708orb1306993PLGA7520AKOS024418768DA-76954FP166703TS-08062T19521

Database identifiers

CAS: 34346-01-5
PubChem CID: 36797

Properties

Computed structural properties

Topological polar surface area: 115 Å²
Hydrogen bond donors: 4
Hydrogen bond acceptors: 6
Rotatable bonds: 2
Heavy atoms: 11
Formal charge: 0
Complexity: 99

Physicochemical properties

Melting point: 262 °C · 262 °C(lit.)
Density: 1.53 g/mL · 1.53 g/mL at 25 °C(lit.)
storage temp.: 2 · 2-8°C
solubility: 100 mg/mL · DMSO : 100 mg/mL ;chloroform : 16.67 mg/mL ;Water : < 0.1 mg/mL (insoluble)
form: Solid
color: White to off-white
optical activity: 0 °, · [α]/D 0°, c =0.5% in chloroform
Modulus of Elasticity: 8.6 GPa, · 8.60 GPa, Fiber
EWG's Food Scores: 1 · 1
FDA UNII: 51 L8Z461QZ · 51L8Z461QZ
UNSPSC Code: 12162002 · 12162002
NACRES: 23 · NA.23
WGK Germany: 3 · 3
F: 10 · 10-21

Safety & regulation

Hazard information

Regulatory InformationPropanoic acid, 2-hydroxy-, polymer with hydroxyacetic acid: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Regulatory information

Regulatory InformationPropanoic acid, 2-hydroxy-, polymer with hydroxyacetic acid: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Safety data

F: 10-21
wgk: 3

Chemistry & industry

Applications · 4 items

DescriptionPoly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds. By poly (D-lactide） made products biological compatibility is good, after the in vivo degradation product by the metabolism out of the body, no harmful and toxic side effects on the human body.

UsesPoly D-lactide is a bioabsorbable and degradable material. Poly D-lactide can be used in medical fields, such as disposable infusion devices, non-removable surgical sutures; controlled release and slow release packaging agents; tissue engineering scaffolds, bone fixation and bone repair materials, microcapsules for injection, microspheres, implant And animal organs support elastomers and other materials. At present, it is widely used in the fields of medicine, such as disposable infusion apparatus, free disassembly type suture; drug controlled release, sustained release agent packaging; scaffolds for tissue engineering, bone fixation and bone repairing material, injection with of microcapsules and microspheres, implants and animal organs elastomer material support.

UsesSurgical aid (surgical suture material, absorbable).

UsesUsed in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.