Prothiofos

HCID 36870
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Basic information

CAS
34643-46-4
Standard SMILES
CCCSP(=S)(OCC)Oc1ccc(Cl)cc1Cl
InChIKey
FITIWKDOCAUBQD-UHFFFAOYSA-N
Molecular formula
C11H15Cl2O2PS2
Average molar mass
345.2 g/mol
Monoisotopic mass
343.9628144

Names & identifiers

Preferred name
Prothiofos
IUPAC
(2,4-dichlorophenoxy)-ethoxy-propylsulfanyl-sulfanylidene-lambda5-phosphane
English name
Prothiofos
Molecular formula
C11H15Cl2O2PS2
Molecular weight
345.25

Names & synonyms

ProthiofosPROTHIOPHOSTokuthion34643-46-4DichlorpropaphosToyodanBAY-NTN 8629DTXSID8042349Phosphorodithioic acid, O-(2,4-dichlorophenyl) O-ethyl S-propyl estero-(2,4-Dichlorophenyl) o-ethyl S-propyl phosphorodithioateH5232196GPDTXCID6022349
Show more names
Tokutionntn-8629toyothionbayntn8629Tokuthhion
CHEBI:38873O-(2,4-dichlorophenyl) O-ethyl S-propyl phosphorodithionateTukuthion(RS)-(O-2,4-DICHLOROPHENYL O-ETHYL S-PROPYL PHOSPHORODITHIOATE)RefChem:176651252-125-7685-654-0Bideron

Database identifiers

CAS
34643-46-4
PubChem CID
36870
DTXSID
DTXSID8042349
ChEMBL
CHEMBL1560680
ChEBI
CHEBI:38873
UNII
H5232196GP
EC Number
252-125-7、685-654-0
Nikkaji
J3.495I

Properties

Computed structural properties

XLogP
4.9
Topological polar surface area
75.9 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
4
Rotatable bonds
7
Heavy atoms
18

Experimental & physicochemical properties

Kovats Retention Index · 3 items

2093；2095；2129；2157；2157.2；2133.2；2101；2133.7；2125.7；2105；2120

2170；2153.3；2155.1；2160.8；2151.7；2150.6

2915

Physicochemical properties

Melting point
25 °C · 25°C
Boiling point
126.5 °C · 126.5 °C
Density
1.3 · 1.3000
vapor pressure
3 · 3.0×10-4 Pa (20 °C)
storage temp.
4 °C · APPROX 4°C
Water Solubility
0.07 mg · 0.07 mg l-1(20 °C)

Safety & regulation

GHS classification

GHS Classification · 6 items

Danger

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H330 (92.9%): Fatal if inhaled [Danger Acute toxicity, inhalation]；H400 (92.9%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410 (92.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P260, P264, P270, P271, P273, P284, P301+P317, P304+P340, P316, P320, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 42 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Not Classified

Hazard information

Regulatory Information · 3 items

Hazard Traits - Environmental tox；Authoritative List - CWA 303(d)；Report - if used as a fragrance or flavor ingredient

2002/2076

Prothiofos: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Phosphorodithioic acid, O-(2,4-dichlorophenyl) O-ethyl S-propyl ester: Human health tier I assessment；IMAP assessments - Phosphorodithioic acid, O-(2,4-dichlorophenyl) O-ethyl S-propyl ester: Environment tier I assessment
Hazard Classes and Categories · 2 items

Acute Tox. 4 (100%)；Acute Tox. 1 (92.9%)；Aquatic Acute 1 (92.9%)；Aquatic Chronic 1 (92.9%)

Acute toxicity (Oral) - Category 4；Acute toxicity (Dermal) - Category 5；Serious eye damage/eye irritation - Category 2B；Skin sensitization - Category 1；Specific target organ toxicity - Single exposure - Category 2 (nervous system)；Hazardous to the aquatic environment (Acute) - Category 1；Hazardous to the aquatic environment (Long-term) - Category 1

Regulatory information

Regulatory Information · 3 items

Hazard Traits - Environmental tox；Authoritative List - CWA 303(d)；Report - if used as a fragrance or flavor ingredient

2002/2076

Prothiofos: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Safety data

wgk
3
rtecs
TD5680000
ridadr
UN 3082
risk_code
22-50/53
Signal word
Danger
Symbol(GHS)
GHS06,GHS09

Chemistry & industry

Uses & manufacturing

Use ClassificationPharmaceuticals
Applications · 2 items

DescriptionProthiofos is a colorless liquid. It is nearly insoluble in water (1.7 mg/L at 20 C) but readily soluble in most organic solvents. Log Kow = 5.67. It is relatively stable in aqueous media; DT50 values (22 C) at pH 4, 7, and 9 are 120, 280, and 12 d, respectively.

UsesProthiofos is used to control chewing insects in a range of crops including vegetables, fruit, maize, sugar cane and ornamentals.

Upstream & downstream products

Suppliers40 total

湖北万得化工有限公司15377098680 15377098680 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海艾梯西生物科技有限公司18721763493

Additional notes

DefinitionChEBI: An organic thiophosphate that is the 2,4-dichlorophenyl ester of O-ethyl S-propyl dithiophosphoric acid.

Related reactions

1 records
New reaction record

Compound notes

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