Cetyl Lactate
Basic information
- CAS
35274-05-6- Standard SMILES
CCCCCCCCCCCCCCCCOC(=O)C(C)O- InChIKey
WUKXMJCZWYUIRZ-UHFFFAOYSA-N- Molecular formula
- C19H38O3
- Average molar mass
- 314.5 g/mol
- Monoisotopic mass
- 314.28209507
Overview
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Cetyl Lactate...
Names & identifiers
- Preferred name
- Cetyl Lactate
- IUPAC
- hexadecyl 2-hydroxypropanoate
- English name
- CETYL LACTATE
- Molecular formula
- C19H38O3
- Molecular weight
- 314.5
Names & synonyms
CETYL LACTATE35274-05-6Hexadecyl lactatePropanoic acid, 2-hydroxy-, hexadecyl estern-Hexadecyl lactateA7EVH2RK4OUNIESTER LCCETINOL LADERMOL CLDUB LCAEC CETYL LACTATELACTABASE C16
Show more names
DHL-C70Ceraphyl 28Liponate CLCtetyl lactatePalmityl lactateHexadecylLactate>CH3CH(OH)COO(CH2)15CH3
NIKKOL CETYL LACTATEFEMA NO. 4483DTXSID20865759RefChem:124715DTXCID40814128252-478-7hexadecyl 2-hydroxypropanoateUNII-A7EVH2RK4O
Database identifiers
- CAS
35274-05-6- PubChem CID
- 37098
- DTXSID
DTXSID20865759- UNII
- A7EVH2RK4O
- EC Number
- 252-478-7
- Nikkaji
- J260.566J
Properties
Computed structural properties
- XLogP
- 7.6
- Topological polar surface area
- 46.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 17
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 241
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Cetyl Lactate) -> CIR (Cosmetic Ingredient Review)
Emollient
Food AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Solubility
Practically insoluble or insoluble in water
Soluble (in ethanol)
Physical DescriptionWhite solid; Faint fatty butter-like aroma
Physicochemical properties
- Melting point
- 41 °C · 41 °C
- Boiling point
- 0.1 · bp0.1 132°; bp1 170°; bp10 219°
- Density
- 1.0196 · 1.0196 (rough estimate)
- vapor pressure
- 0 Pa · 0Pa at 25℃
- refractive index
- 40 · nD40 1.4410; nD50 1.4370
- FEMA
- 4483 · 4483 | HEXADECYL LACTATE
- pka
- 13.05 · 13.05±0.20(Predicted)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 95.7% (67 of 70) of all reports.
Not Classified
Aggregated GHS information provided per 70 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
Chemical: Propanoic acid, 2-hydroxy-, hexadecyl ester
REACH registered substance: Hexadecyl lactate (EC: 252-478-7)
Propanoic acid, 2-hydroxy-, hexadecyl ester: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesNot Classified
Toxicology
Toxicity Summary
Based on the available information included in this report, the CIR Expert Panel concludes that Glycolic and Lactic Acid, their common salts and their simple esters, are safe for use in cosmetic products at concentrations less than or equal to 10%, at final formulation pH greater than or equal to 3.5, when formulated to avoid increasing sun sensitivity or when directions for use include the daily use of sun protection. These ingredients are safe for use in salon products at concentrations less than or equal to 30%, at final formulation pH greater than or equal to 3.0, in products designed for brief, discontinuous use followed by thorough rinsing from the skin, when applied by trained professionals, and when application is accompanied by directions for the daily use of sun protection...Cetyl Lactate...
Safe for use in cosmetics, with qualifications
Safety data
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Cetyl Lactate
Household ProductsInformation on 4 consumer products that contain Cetyl lactate in the following categories is provided:
Use Classification
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Flavoring Agents -> JECFA Flavorings Index
Cosmetics -> Emollient
General Manufacturing InformationPropanoic acid, 2-hydroxy-, hexadecyl ester: ACTIVE
Applications
UsesNonionic emollient. To improve feel and texture of cosmetic and pharmaceutical preparations.
Upstream & downstream products
Upstream raw materials
Additional notes
DefinitionCetyl Lactate, an ester derived from cetyl alcohol and lactic acid, is valued in various industries for its emollient, moisturizing, and conditioning properties.
Suppliers
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Related reactions
2 records
Compound notes
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