Basic information
- CAS
35795-16-5- Standard SMILES
COc1cc2c(N)nc(N3CCN(C(=O)OCC(C)(C)O)CC3)nc2c(OC)c1OC- InChIKey
YNZXWQJZEDLQEG-UHFFFAOYSA-N- Molecular formula
- C20H29N5O6
- Average molar mass
- 435.5 g/mol
- Monoisotopic mass
- 435.21178366
Overview
Trimazosin is a N-arylpiperazine.
Names & identifiers
- Preferred name
- Trimazosin
- IUPAC
- (2-hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate
- English name
- Trimazosin
- Molecular formula
- C20H29N5O6
- Molecular weight
- 435.47
Names & synonyms
TRIMAZOSIN35795-16-5TrimazosineTrimazosinumtrimazosina31L760807HDTXSID501893192-hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate4-(4-Amino-6,7,8-trimethoxy-2-quinazolinyl)-1-piperazinecarboxylic acid, 2-hydroxy-2-methylpropyl ester2-hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxy-2-quinqzolinyl)-1-piperazinecar boxylateCP-19,106RefChem:191718
Show more names
C005185Cp 19,1064-(4-Amino-6,7,8-trimethoxyquinazolin-2-yl)-1-piperazinecarboxylic acid 2-hydroxy-2-methylpropyl ester4-(4-Amino-6,7,8-trimethoxy-2-quinazolinyl)-1-piperazinecarboxylic acid, 2-hydroxy-2- methylpropyl ester1-Piperazinecarboxylic acid, 4-(4-amino-6,7,8-trimethoxy-2-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester
C02CA03DTXCID30111810252-732-7(2-hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylateTrimazosin (INN)TRIMAZOSIN [INN]TrimazosinoTrimazosin [INN:BAN]
Database identifiers
- CAS
35795-16-5- PubChem CID
- 37264
- DTXSID
DTXSID50189319- ChEMBL
CHEMBL513301- ChEBI
CHEBI:135710- UNII
- 31L760807H
- EC Number
- 252-732-7
- Nikkaji
- J19.681I
Properties
Computed structural properties
- XLogP
- 1.2
- Topological polar surface area
- 133 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 7
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 603
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
LogP1.3
Physicochemical properties
- Melting point
- 158 · 158-159°
- FDA UNII
- 31 L760807H · 31L760807H
- ATC code
- 2 CA03 · C02CA03
Chemistry & industry
Pharmacology
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Drugs used to cause dilation of the blood vessels.
Drugs that bind to and block the activation of ADRENERGIC ALPHA-1 RECEPTORS.
Applications
UsesAntihypertensive.
Suppliers2 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Additional notes
DefinitionChEBI: Trimazosin is a N-arylpiperazine.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…