Imidazole Salicylate
Basic information
- CAS
36364-49-5- Standard SMILES
O=C(O)c1ccccc1O.c1c[nH]cn1- InChIKey
XCHHJFVNQPPLJK-UHFFFAOYSA-N- Molecular formula
- C10H10N2O3
- Average molar mass
- 206.2 g/mol
- Monoisotopic mass
- 206.06914219
Overview
2-hydroxybenzoic acid compounded with imidazole
Names & identifiers
- Preferred name
- Imidazole Salicylate
- IUPAC
- 2-hydroxybenzoic acid;1H-imidazole
- English name
- Imidazole
- Molecular formula
- C10H10N2O3
- Molecular weight
- 0
Names & synonyms
Imidazole salicylate36364-49-5SelezenImidazole-2-hydroxybenzoateSalicilato de imidazolSalicylate d'imidazoleImidazoli salicylasITF-1824JVD4X01MJDTXSID80189887salizoleRefChem:790725
Show more names
IMIDAZOLE SALICYLATE USP/EP/BP
DTXCID40112378N02BA161H-imidazole; 2-hydroxybenzoic acid1H-imidazole 2-hydroxybenzoateImidazole 2-hydroxybenzoateImidazole salicylate [INN]2-hydroxybenzoic acid;1H-imidazoleSalizolo
Database identifiers
- CAS
36364-49-5- PubChem CID
- 37425
- DTXSID
DTXSID80189887- ChEMBL
CHEMBL2104788- UNII
- 4JVD4X01MJ
- EC Number
- 641-575-3
Properties
Computed structural properties
- Topological polar surface area
- 86.2 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 161
Physicochemical properties
- Melting point
- 123 · 123-124°
- FDA UNII
- 4 JVD4X01MJ · 4JVD4X01MJ
- Toxicity
- 50 in · LD50 in male, female rats, mice (mg/kg): 763, 724, 595, 685 s.c.; 422, 434, 462, 435 i.v.; 1211, 1430, 1034, 1091 orally (Pagella)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Safety data
- Toxicity
- LD50 in male, female rats, mice (mg/kg): 763, 724, 595, 685 s.c.; 422, 434, 462, 435 i.v.; 1211, 1430, 1034, 1091 orally (Pagella)
Chemistry & industry
Pharmacology
ATC Code
N - Nervous system
QN - Nervous system
MeSH Pharmacological Classification
Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.
Applications
UsesImidazole salicylate (Standard) is the analytical standard of Imidazole salicylate. This product is intended for research and analytical applications. Imidazole salicylate is a nonsteroidal anti-inflammatory drug that can be used to study cirrhosis and ascites.
Suppliers
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Related reactions
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Compound notes
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