Pipotiazine Palmitate
Basic information
- CAS
37517-26-3- Standard SMILES
CCCCCCCCCCCCCCCC(=O)OCCC1CCN(CCCN2c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1- InChIKey
KTOYYUONFQWSMW-UHFFFAOYSA-N- Molecular formula
- C40H63N3O4S2
- Average molar mass
- 714.1 g/mol
- Monoisotopic mass
- 713.42599985
Overview
Pipotiazine palmitate is a member of phenothiazines.
Names & identifiers
- Preferred name
- Pipotiazine Palmitate
- IUPAC
- 2-[1-[3-[2-(dimethylsulfamoyl)phenothiazin-10-yl]propyl]piperidin-4-yl]ethyl hexadecanoate
- English name
- Pipotiazine palmitate
- Molecular formula
- C40H63N3O4S2
- Molecular weight
- 714.08
Names & synonyms
PIPOTIAZINE PALMITATE37517-26-3Pipothiazine palmitatePiportil depotPipotiazine Palmitic EsterRP 19552Pipothiazin palmitateDTXSID504897019552 RPRP-195524Q3H01QRMIIL-19552
Show more names
RP-19366PiportilPiportil L4Palmitic esterPIPOTHIAZINEPALMITATE2-[1-[3-[2-[(Dimethylamino)sulfonyl]-10H-phenothiazin-10-yl]propyl]-4-piperidinyl]ethanol2-[1-[3-[2-(dimethylsulfamoyl)phenothiazin-10-yl]propyl]piperidin-4-yl]ethyl hexadecanoate
DTXCID802889610-(3-(4-(2-Hydroxyethyl)piperidino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide palmitate (ester)Hexadecanoic acid, 2-(1-(3-(2-((dimethylamino)sulfonyl)-10H-phenothiazin-10-yl)propyl)-4-piperidinyl)ethyl ester10-[3-[4-(2-Hydroxyethyl)piperidino]propyl]-N,N-dimethylphenothiazine-2-sulfonamide palmitate (ester)RefChem:174475253-536-4IL 19552Pipotiazine palmitate [USAN]
Database identifiers
- CAS
37517-26-3
Properties
Computed structural properties
- XLogP
- 11.6
- Topological polar surface area
- 104 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 24
- Heavy atoms
- 49
- Formal charge
- 0
- Complexity
- 1,010
Physicochemical properties
- Melting point
- 61 · 61-63°C
- Boiling point
- 773.4 · 773.4±70.0 °C(Predicted)
- Density
- 1.09 · 1.090±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.14 · 9.14±0.10(Predicted)
- color
- Yellow
- FDA UNII
- 4 Q3H01QRMI · 4Q3H01QRMI
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 317 · H317-H315-H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P270, P272, P280, P301+P317, P302+P352, P321, P330, P332+P317, P333+P317, P362+P364, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H317-H315-H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
DescriptionPipotiazine palmitate, a long-acting antipsychotic generally administered as an injection and not available as an oral medication, was withdrawn globally in March 2015 in favour of other antipsychotic medications due to a shortage of its active ingredient.
UsesAntipsychotic.
UsesPipotiazine palmitate is an antipsychotic medication used for the maintenance treatment of patients with chronic non agitated schizophrenia.
Additional notes
DefinitionChEBI: Pipotiazine palmitate is a member of phenothiazines.
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…