Basic information
- CAS
39543-79-8- Standard SMILES
CC(=O)c1cc2cccc(OCC(O)C[NH2+]C(C)C)c2o1.[Cl-]- InChIKey
TVVTWOGRPVJKDJ-UHFFFAOYSA-N- Molecular formula
- C16H22ClNO4
- Average molar mass
- 327.8 g/mol
- Monoisotopic mass
- 327.1237359
Overview
Befunolol hydrochloride is a member of benzofurans.
Names & identifiers
- Preferred name
- Glauconex
- IUPAC
- [3-[(2-acetyl-1-benzofuran-7-yl)oxy]-2-hydroxypropyl]-propan-2-ylazanium chloride
- English name
- Befunolol hydrochloride
- Molecular formula
- C16H22ClNO4
- Molecular weight
- 0
Names & synonyms
GlauconexBefunolol hydrochloride [JAN]Bentox[3-[(2-acetyl-1-benzofuran-7-yl)oxy]-2-hydroxypropyl]-propan-2-ylazanium;chlorideBefunolol hydrochloride (JAN)BFE 60UNII-B03Z2VY37IBentos (TN)2-Acetyl-7-((2-hydroxy-3-isopropylamino)propoxy)benzofuran hydrochlorideCHEBI:31254Ethanone, 1-(7-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-2-benzofuranyl)-, hydrochlorideD01512
Show more names
BentosBenfuranBefunolol HClBefunolol hydrochloride2-Acetyl-7-[2-hydroxy-3-(isopropylamino)propoxy]benzofuran hydrochlorideEthanone, 1-[7-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-2-benzofuranyl]-, hydrochloride
1-[7-[2-hydroxy-3-(propan-2-ylamino)propoxy]-1-benzofuran-2-yl]ethanone;hydrochloride
Database identifiers
- CAS
Properties
Computed structural properties
- Topological polar surface area
- 76.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 7
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 347
Physicochemical properties
- Melting point
- 163 ° · 163°
- form
- Liquid eye medication
- FDA UNII
- 3 Z2VY37I · B03Z2VY37I
- Toxicity
- 50 oral · LD50 oral in rabbit: 400mg/kg
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 oral in rabbit: 400mg/kg
Chemistry & industry
Applications
DescriptionBefunolol hydrochloride is the newest of the 8-adrenergic blockers to be introduced for the treatment of glaucoma. It is reportedly devoid of intrinsic sympathomimetic activity, with lower membrane-stabilizing activity than propranolol.
Suppliers6 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
湖北扬信医药科技有限公司0714-3999001 19171453112 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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