Basic information
- CAS
58822-25-6- Standard SMILES
CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)O- InChIKey
URLZCHNOLZSCCA-UHFFFAOYSA-N- Molecular formula
- C28H37N5O7
- Average molar mass
- 555.6 g/mol
- Monoisotopic mass
- 555.26929854
Overview
2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxoethyl]amino]-1-oxoethyl]amino]-1-oxo-3-phenylpropyl]amino]-4-methylpentanoic acid is a peptide.
Names & identifiers
- Preferred name
- Leucine enkephalin
- IUPAC
- 2-[[2-[[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
- English name
- [LEU5]-ENKEPHALIN
- Molecular formula
- C28H37N5O7
- Molecular weight
- 555.62
Names & synonyms
leucine enkephalinTyr-Gly-Gly-Phe-LeuYGGFL1-5-b-Neoendorphin (human)C28H37N5O7Leu-Enkephalin acetate saltNSC350588NSC-350588[Leu]-enkephalinSpectrum_001429Spectrum2_001177Spectrum3_001521
Show more names
LEU-ENKEPHALINENKEPHALIN LLEUCINE-ENKEPHALINamide acetateLeu-Enkelphalin[LEU5]-ENKEPHALINDYNORPHIN A (1-5)Leucyl-enkephalinenkephalin,leucine
Spectrum4_001048Spectrum5_000656BSPBio_002902KBioGR_001316KBioSS_001909DivK1c_001010SCHEMBL631958SPBio_001193
Database identifiers
- CAS
58822-25-6- PubChem CID
- 3903
- ChEBI
CHEBI:91634
Properties
Computed structural properties
- XLogP
- -2.3
- Topological polar surface area
- 200 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 15
- Heavy atoms
- 40
- Formal charge
- 0
- Complexity
- 854
Physicochemical properties
- Melting point
- 130 · 130-133 °C
- alpha
- 32.3 ° · +32.3°(c=9,メタノール)
- Boiling point
- 998.8 · 998.8±65.0 °C(Predicted)
- Density
- 1.274 · 1.274±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- solubility
- 54.6 mg/mL · ≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO
- form
- Lyophilized powder
- pka
- 3.4 · 3.40±0.10(Predicted)
- color
- White to light yellow
- Water Solubility
- Soluble in water (1 mg/ml ).
- Sequence
- H-Tyr-Gly-Gly-Phe-Leu-OH
- InChIKey
- URLZCHNOLZSCCA-VABKMULXSA-N
- SMILES
- C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N
- FDA UNII
- 1 R707R6 · RI01R707R6
- Safety Statements
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 3-10-21
- wgk
- 3
- safety_code
- 22-24/25
Chemistry & industry
Applications
UsesEndogenous opioid neurotransmitter/neuromodulator that is an agonist at and δ opioid receptors, localization in brain parallels the localization of δ receptors.
Suppliers100 total
湖北省文鑫生物科技有限公司+86-15387208865 +86-15387208865 · [email protected] [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
陕西缔都化学有限公司029-029-81123119 17391733320 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
张家港阿拉宁生化技术有限公司512-58900862 400-0707518 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
Related reactions
3 records
Compound notes
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