Basic information
- CAS
21306-56-9- Standard SMILES
CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C- InChIKey
PYEBKOFMWAMBFV-UHFFFAOYSA-O- Molecular formula
- C16H27N2O+
- Average molar mass
- 263.4 g/mol
- Monoisotopic mass
- 263.21233849
Overview
QX-314 is a monocarboxylic acid amide. It has a role as a local anaesthetic.
Names & identifiers
- Preferred name
- 2-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium
- IUPAC
- [2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium
- English name
- QX-314
- Molecular formula
- C16H27N2O+
- Molecular weight
- 263.4
Names & synonyms
QX-314QX 31446ZIF6Y2X9CHEBI:469372-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminiumDTXSID10943813(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-triethylazanium[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-triethylazaniumRefChem:178402DTXCID50137217621306-56-9
Show more names
LIDOCAINE N-ETHYL BROMIDEQX-314.BrQX 314 BROMIDEQX 314, 10 mM in DMSOLidocaine N-ethyl bromidLidocaine N-ethyl bromideQX-314 - CAS 21306-56-9 - CalbiochemQX 314 BROMIDE,LIDOCAINE N-ETHYL BROMIDQX-314 bromide (N-Ethyllidocaine bromide)
N-ETHYLLIDOCAINE BROMIDECHEMBL128028Tocris-1014Lopac-L-5783UPCMLD-DP014UNII-46ZIF6Y2X9Lopac0_000679SCHEMBL93854
Database identifiers
Properties
Computed structural properties
- XLogP
- 2.5
- Topological polar surface area
- 29.1 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 6
- Heavy atoms
- 19
- Formal charge
- 1
- Complexity
- 268
Physicochemical properties
- Melting point
- 220 · 220 - 222°C
- storage temp.
- Desiccate at RT
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- lyophilized solid
- color
- White to Off-White
- Water Solubility
- 3 mg/mL · water: 3mg/mL
- Specific Activity
- 40 · 40-60 Ci/mmol
- Solvent
- Ethanol:water (1:1)
- Concentration
- 1 mCi/ml · 1 mCi/ml
- Major Application
- forensics and toxicologypharmaceutical (small molecule)veterinary
- InChI
- 1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
- InChIKey
- DLHMKHREUTXMCH-UHFFFAOYSA-N
- SMILES
- [Br-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
- FDA UNII
- 46 ZIF6Y2X9 · 46ZIF6Y2X9
- UNSPSC Code
- 41116107 · 41116107
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Applications
UsesBlocker of voltage-activated sodium channels
UsesQX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.
Suppliers30 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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