Basic information
- CAS
146555-78-4- Standard SMILES
Cn1cc2c3c1C(=O)C(N)=CC3=NCC2- InChIKey
RUIRYCQUTHWLMZ-UHFFFAOYSA-N- Molecular formula
- C11H11N3O
- Average molar mass
- 201.22 g/mol
- Monoisotopic mass
- 201.09021198
Overview
Makaluvamine A has been reported in Zyzzya fuliginosa, Zyzzya, and Didymium bahiense with data available.
Names & identifiers
- Preferred name
- Makaluvamine A
- IUPAC
- 10-amino-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,7,9-tetraen-11-one
- English name
- makaluvamine A
- Molecular formula
- C11H11N3O
- Molecular weight
- 201.22
Names & synonyms
Makaluvamine A146555-78-4DTXSID1016339710-amino-2-methyl-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(12),3,7,9-tetraen-11-one10-amino-2-methyl-2,7-diazatricyclo(6.3.1.04,12)dodeca-1(12),3,7,9-tetraen-11-oneRefChem:155331DTXCID4085888Pyrrolo(4,3,2-de)quinolin-8(1H)-one, 7-amino-3,4-dihydro-1-methyl-7-Amino-1-methyl-3,4-dihydropyrrolo[4,3,2-de]quinolin-8(1H)-onePyrrolo[4,3,2-de]quinolin-8(1H)-one, 7-amino-3,4-dihydro-1-methyl-starbld0004927Pyrrolo[4,3,2-de]quinolin-8(1H)-one,7-amino-3,4-dihydro-1-methyl-
Show more names
7-Amino-3,4-dihydro-1-methylpyrrolo[4,3,2-de]quinolin-8(1H)-one
CHEMBL449905orb1738888SCHEMBL9262213NSC700008NSC 700008NSC-700008HY-125580B725050K179
Database identifiers
- CAS
146555-78-4
Properties
Computed structural properties
- XLogP
- 0
- Topological polar surface area
- 60.4 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 0
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 385
Physicochemical properties
- Boiling point
- 385.4 · 385.4±42.0 °C(Predicted)
- Density
- 1.51 · 1.51±0.1 g/cm3(Predicted)
- pka
- 5 · 5.00±0.20(Predicted)
Chemistry & industry
Applications
DescriptionMakaluvamine A comes from the fruiting bodies of Didymium bahiense that act as active anti-cancer agents and DNA topo II inhibitors.
UsesMakaluvamine A is a member of Makaluvamines. Makaluvamines can be isolated from Fijian sponges of the genus Zyzzya, and possess inhibitory activity toward topoisomerase II along with cytotoxic activity against HCT-116 human colon cancer cells[1].
Suppliers2 total
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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