Basic information
- CAS
1227-61-8- Standard SMILES
CCN(CC)CCNC(=O)COc1ccc(OC)cc1- InChIKey
HUNIPYLVUPMFCZ-UHFFFAOYSA-N- Molecular formula
- C15H24N2O3
- Average molar mass
- 280.36 g/mol
- Monoisotopic mass
- 280.17869263
Overview
N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide is a member of methoxybenzenes.
Names & identifiers
- Preferred name
- Mefexamide
- IUPAC
- N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamide
- English name
- Mefexamide hydrochloride
- Molecular formula
- C15H24N2O3
- Molecular weight
- 280.36
Names & synonyms
mefexamide1227-61-8TimodyneMexephenamideMefexadyneMefexamidaMefexamidumAcetamide, N-(2-(diethylamino)ethyl)-2-(4-methoxyphenoxy)-DTXSID504847584FP054Z2QN-(2-(Diethylamino)ethyl)-2-(p-methoxyphenoxy)acetamideacetamide, n-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)-
Show more names
mp297np297anp297u-25701amefaxadyneMEFEXAMIDE HCL
NSC-757827mefaxamidmefessamideRefChem:810849DTXCID1028449214-963-1N-[2-(diethylamino)ethyl]-2-(4-methoxyphenoxy)acetamideMephexamide
Database identifiers
- CAS
1227-61-8- PubChem CID
- 4045
- DTXSID
DTXSID5048475- ChEMBL
CHEMBL1368380- ChEBI
CHEBI:92373- UNII
- 84FP054Z2Q
Properties
Computed structural properties
- XLogP
- 2
- Topological polar surface area
- 50.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 9
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 262
Experimental & physicochemical properties
Solubility32 [ug/mL] (The mean of the results at pH 7.4)
Human DrugsPharmaceuticals
Collision Cross Section
171.2 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
169.86 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- Boiling point
- 423.08 °C · 423.08°C (rough estimate)
- Density
- 1.0586 · 1.0586 (rough estimate)
- refractive index
- 1.58 · 1.5800 (estimate)
- storage temp.
- -20 °C · Store at -20°C
- solubility
- Soluble in DMSO
- Major Application
- forensics and toxicologypharmaceutical (small molecule)veterinary
- InChI
- 1S/C15H24N2O3.ClH/c1-4-17(5-2)11-10-16-15(18)12-20-14-8-6-13(19-3)7-9-14;/h6-9H,4-5,10-12H2,1-3H3,(H,16,18);1H
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]
P260, P262, P264, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 2 (100%)
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
- wgk
- 3
- rtecs
- AB7175000
- ridadr
- UN 2811 6.1/PG 1
- risk_code
- 26/27/28
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- T+
- safety_code
- 22-36/37/39-45
- Storage Class
- 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials
- Hazard statements
- H300+H310+H330
- Hazard Classifications
- Acute Tox. 2 Oral
- Precautionary statements
- P260-P262-P264-P280-P302+P352+P310-P304+P340+P310
Chemistry & industry
Uses & manufacturing
Use ClassificationPharmaceuticals
Applications
UsesCNS stimulant
Suppliers20 total
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
Aladdin Scientific[email protected]
MedChemexpress LLC021-58955995 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
上海颖心实验室设备有限公司021-021-59178156 15300768757 · [email protected]
爱必信（上海）生物科技有限公司13761418683 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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