Basic information
- CAS
71125-39-8- Standard SMILES
Cc1cnc(NC(=O)C2=C([O-])c3ccccc3S(=O)(=O)N2C)s1.[Na+]- InChIKey
PTCPMRKGGUPNDO-UHFFFAOYSA-M- Molecular formula
- C14H12N3NaO4S2
- Average molar mass
- 373.4 g/mol
- Monoisotopic mass
- 373.0166925
Names & identifiers
- Preferred name
- Meloxicam Sodium
- IUPAC
- sodium 2-methyl-3-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,1-dioxo-1λ6,2-benzothiazin-4-olate
- English name
- MELOXICAM SODIUM SALT HYDRATE
- Molecular formula
- C14H12N3NaO4S2
- Molecular weight
- 374.39
Names & synonyms
Meloxicam sodiumDTXSID601017452RefChem:156430DTXCID40147624871125-39-8MELOXICAM (SODIUM)Sodium 2-methyl-3-((5-methylthiazol-2-yl)carbamoyl)-2H-benzo[e][1,2]thiazin-4-olate 1,1-dioxidesodium 2-methyl-3-[(5-methyl-1,3-thiazol-2-yl)carbamoyl]-1,1-dioxo-2H-1lambda6,2-benzothiazin-4-olateNCGC00015671-01Lopac-M-3935MLS002153247orb1688527
Show more names
Meloxicam sodium saltMobec sodium salt hydrateMetacam sodium salt hydrateFRMZBLMVNUXMTO-UHFFFAOYSA-NMELOXICAM SODIUM SALT HYDRATEUH-AC 62XX sodium salt hydrateMeloxicam hydrate sodium salt4-hydroxy-2-methyl-n-(5-methyl-2-thiazolyl)-2h-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrateMeloxicam sodium salt hydrate,4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide sodium hydrate, Metacam sodium salt hydrate, Mobec sodium salt hydrate, UH-AC 6Metacam hydrate sodium salt, Mobec hydrate sodium salt, UH-AC 62XX hydrate sodium salt, 4-Hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide hydrate sodium
Properties
Computed structural properties
- Topological polar surface area
- 139 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 2
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 634
Experimental & physicochemical properties
Solubility>56 [ug/mL] (The mean of the results at pH 7.4)
Collision Cross Section174.5 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
Physicochemical properties
- storage temp.
- room temp
- solubility
- 5 mg/mL, · DMSO: soluble5mg/mL, clear
- form
- powder
- color
- light yellow to dark yellow
- InChI
- 1S/C14H13N3O4S2.Na.H2O/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2;;/h3-7,18H,1-2H3,(H,15,16,19);;1H2/q;+1;/p-1
- InChIKey
- IZBZAOZGNNQKPJ-UHFFFAOYSA-M
- SMILES
- O.[Na+].CN1C(C(=O)Nc2ncc(C)s2)=C([O-])c3ccccc3S1(=O)=O
- UNSPSC Code
- 51111800 · 51111800
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- ridadr
- UN 2811 6.1/PG 3
- risk_code
- 22-36/37/38
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_code
- Xn
- safety_code
- 26
- Storage Class
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- target organs
- Respiratory system
- Hazard statements
- H301-H315-H319-H335
- Hazard Classifications
- Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P301+P310+P330-P302+P352-P305+P351+P338
Chemistry & industry
Applications
UsesMeloxicam sodium salt hydrate has been used: as a cyclooxygenase-2 (COX-2) inhibitor in solid Ehrlich tumoras an alternative to diclofenac nonsteroidal anti-inflammatory drugs (NSAID) to treat vulturesas a reference standard in liquid chromatography electrospray ionisation mass spectrometry (LC-ESI/MS)to test its effect on prostaglandin (PGE2) production in lipopolysaccharide (LPS)-induced COX-2 protein expression in RAW246.7 cells
Suppliers8 total
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
Related reactions
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Compound notes
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