Basic information
- CAS
84-21-9- Standard SMILES
Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](OP(=O)(O)O)[C@H]1O- InChIKey
LNQVTSROQXJCDD-KQYNXXCUSA-N- Molecular formula
- C10H14N5O7P
- Average molar mass
- 347.22 g/mol
- Monoisotopic mass
- 347.0630848
Overview
3'-AMP is an adenosine 3'-phosphate with a monophosphate group at the 3'-position. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a purine ribonucleoside 3'-monophosphate and an adenosine 3'-phosphate. It is a conjugate acid of a 3'-AMP(2-).
Names & identifiers
- Preferred name
- Adenosine 3'-Phosphate
- IUPAC
- [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate
- English name
- 3'-Adenylic acid
- Molecular formula
- C10H14N5O7P
- Molecular weight
- 347.22
Names & synonyms
Adenosine 3'-phosphateRefChem:484603CHEBI:370973'-Adenylic acid84-21-9Adenosine 3'-monophosphateSynadenylic acid3'-AMPYeast adenylic acidAdenosine-3'-monophosphateAdenosine-3'-phosphateAdenosine-3'-monophosphoric acid
Show more names
CD62GMRPGRMPPSELC01367A-3'-MPAdo-3'-Pfromyeast
AMP 3'-phosphate3'-Adenosine monophosphateAdenosine 3'-phosphate monohydrateAdenosine-3'-phosphoric acid[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphateCHEMBL576739R438H7I3KZ{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}phosphonic acid
Database identifiers
- CAS
84-21-9- PubChem CID
- 41211
- DTXSID
DTXSID40876084- ChEMBL
CHEMBL576739
Properties
Computed structural properties
- XLogP
- -2.7
- Topological polar surface area
- 186 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 11
- Rotatable bonds
- 4
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 481
Experimental & physicochemical properties
LogP
-1.453
-2.98
Solubility500 mg/L at 15 °C
Melting Point197 °C
Physical DescriptionSolid
Collision Cross Section171.18 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]
Physicochemical properties
- Melting point
- 210 °C · ~210 °C (dec.)
- Boiling point
- 815.5 · 815.5±75.0 °C(Predicted)
- Density
- 2.32 · 2.32±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- Aqueous Base (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly)
- pka
- 1 · pK1: 3.65(0);pK2: 5.88(-1) (25°C)
- form
- Solid
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory InformationChemical: 3'-Adenylic acid
Other Safety InformationEvaluation - Chemicals that are unlikely to require further regulation to manage risks to environment
Safety data
- F
- 10-21
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- rtecs
- AU7480320
- safety_code
- 22-24/25
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Pharmacology
Tissue LocationsPlacenta
Metabolite Pathways27-Hydroxylase Deficiency
Uses & manufacturing
General Manufacturing Information3'-Adenylic acid: INACTIVE
Applications
UsesAdenosine 3′-monophosphate (3′-AMP) is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.
Suppliers63 total
北京华美互利生物化工010-56205725 · [email protected]
南京世洲生物科技有限公司025-85560043 15850508050 · [email protected]
武汉敬康恩生物医药科技有限公司13720134139 086-15871494362 13720134139 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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