N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate

HCID 4170355
NotesReactions
Substructure searchFind similar structures

Basic information

CAS
367927-39-7
Standard SMILES
O=C(CCN1C(=O)C=CC1=O)NCCCCCC(=O)ON1C(=O)CCC1=O
InChIKey
WCMOHMXWOOBVMZ-UHFFFAOYSA-N
Molecular formula
C17H21N3O7
Average molar mass
379.4 g/mol
Monoisotopic mass
379.13795002

Names & identifiers

Preferred name
N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate
IUPAC
(2,5-dioxopyrrolidin-1-yl) 6-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]hexanoate
English name
N-Succinimidyl 6-(3-maleimidopropionamido) hexanoate
Molecular formula
C17H21N3O7
Molecular weight
379.36

Names & synonyms

367927-39-7SMPH CrosslinkerN-Succinimidyl 6-(3-Maleimidopropionamido) HexanoateSMPHMFCD018634602,5-Dioxopyrrolidin-1-yl 6-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)hexanoate(2,5-dioxopyrrolidin-1-yl) 6-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]hexanoate2,5-dioxopyrrolidin-1-yl 6-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]hexanoateWCMOHMXWOOBVMZ-UHFFFAOYSA-NC17H21N3O7SCHEMBL109173orb1988924
Show more names
Succinimidyl-6-[(β-maleimidopropionamido)hexanoate6-(N-[3-MALEIMIDOPROPIONAMIDO])HEXANOATE-SUCCINIMIDE6-(3-Maleimidopropionylamino)-hexanoic acid-NHS esterSMPH (Succinimidyl 6-((beta-maleimidopropionamido)hexanoate))N-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate（SMPH Crosslinker）N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-2,5-dihydro-2,5-dioxo-1H-pyrrole-1-propanamideHexanoic acid, 6-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-, 2,5-dioxo-1-pyrrolidinyl ester
DTXSID80400226SMPH (succinimidyl-6-((b-maleimidopropionamido)hexanoate)AKOS027384368FS278986-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]hexanoic Acid 2,5-Dioxo-1-pyrrolidinyl EsterAS-69227BP-22646DA-67647

Database identifiers

CAS
367927-39-7
PubChem CID
4170355
DTXSID
DTXSID80400226
Nikkaji
J1.988.601H

Properties

Computed structural properties

XLogP
-1.3
Topological polar surface area
130 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
7
Rotatable bonds
11
Heavy atoms
27

Physicochemical properties

storage temp.
2 · 2-8°C
solubility
DMSO or DMF: soluble
form
powder
InChI
1S/C17H21N3O7/c21-12(9-11-19-13(22)5-6-14(19)23)18-10-3-1-2-4-17(26)27-20-15(24)7-8-16(20)25/h5-6H,1-4,7-11H2,(H,18,21)
InChIKey
WCMOHMXWOOBVMZ-UHFFFAOYSA-N
SMILES
O=C(CCCCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O

Safety & regulation

Safety data

wgk
WGK 3
Signal word
Warning
Symbol(GHS)
GHS07
Storage Class
11 - Combustible Solids
target organs
Respiratory system
Hazard statements
H315-H319-H335

Chemistry & industry

Applications · 4 items

DescriptionSMPH Crosslinker is a non-cleavable, water soluble crosslinker containing a maleimide and NHS ester group. The maleimide is able to react with thiol groups between pH 6.5 to 7.5 to form thiolester bonds. NHS ester groups are reactive toward primary amines.

UsesA sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Spacer Arm: 14.3 Angstroms

Usescarbonyl and sulfhydryl reactive heterobifunctional cross-linking reagent

UsesA sulfhydryl and amino reactive heterobifunctional crosslinking reagent.Spacer Arm: 14.3 Angstroms

Suppliers32 total

上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
常州科化生物科技有限公司0519-68985668 13685222090 · [email protected]

Related reactions

1 records
New reaction record

Compound notes

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