Basic information
- CAS
56290-94-9- Standard SMILES
CC(CCc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(C(N)=O)c1- InChIKey
MPQWSYJGFLADEW-UHFFFAOYSA-N- Molecular formula
- C20H24N2O5
- Average molar mass
- 372.4 g/mol
- Monoisotopic mass
- 372.16852187
Overview
Medroxalol is a member of salicylamides.
Names & identifiers
- Preferred name
- Medroxalol
- IUPAC
- 5-[2-[4-(1,3-benzodioxol-5-yl)butan-2-ylamino]-1-hydroxyethyl]-2-hydroxybenzamide
- English name
- 5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]salicylamide
- Molecular formula
- C20H24N2O5
- Molecular weight
- 372.42
Names & synonyms
MEDROXALOL56290-94-9MedroxalolumRMI 81,968RMI-81968RMI 81968Rmi-81,9687PX96289JADTXSID30866550Benzamide, 5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-hydroxy-RefChem:925427DTXCID40814825
Show more names
Medroxalol (Mixture of Diastereomers)5-[2-[[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]-2-hydroxybenzamideBenzamide, 5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]-2-hydroxy-
5-(2-((3-(1,3-benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)-2-hydroxybenzamidebenzamide, 5-(2-((3-(1,3-benzodioxol)-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl-2-hydroxy-5-[2-[4-(1,3-benzodioxol-5-yl)butan-2-ylamino]-1-hydroxyethyl]-2-hydroxybenzamide5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]salicylamide5-(1-Hydroxy-2-((1-methyl-3-(3,4-(methylenedioxy)phenyl)propyl)amino)ethyl)salicylamideRMI 81968;RMI-81968;RMI81968Medroxalolum [INN-Latin]5-(2-((3-(1,3-Benzodioxol-5-yl)-1-methylpropyl)amino)-1-hydroxyethyl)salicylamide
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 2.9
- Topological polar surface area
- 114 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 491
Experimental & physicochemical properties
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- soluble in No data available
- form
- Solid
- color
- Off-white to light yellow
- FDA UNII
- 7 PX96289JA · 7PX96289JA
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs that bind to but do not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. Adrenergic alpha-antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma.
Drugs that bind to but do not activate beta-adrenergic receptors thereby blocking the actions of beta-adrenergic agonists. Adrenergic beta-antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches, and anxiety.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Applications
UsesAntihypertensive.
UsesMedroxalol is an antihypertensive agent that possesses both alpha and beta-adrenergic antagonistic properties. Medroxalol is used to treat mild and moderate hypertension.
Suppliers9 total
江苏艾康生物医药研发有限公司025-66061636 19370895928 · [email protected]
Aladdin Scientific[email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 13028896684 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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