Completing data — refresh the page later to see the latest
Basic information
- CAS
119959-65-8- Standard SMILES
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)NCCS(=O)(=O)O- InChIKey
YUNYSWCRLRYOPO-DOFZRALJSA-N- Molecular formula
- C22H37NO4S
- Average molar mass
- 411.608 g/mol
- Monoisotopic mass
- 411.24432966
Names & identifiers
- Preferred name
- 2-[[(5Z,8Z,11Z,14Z)-1-Oxo-5,8,11,14-eicosatetraen-1-yl]amino]ethanesulfonic acid
- IUPAC
- 2-{[(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoyl]amino}ethane-1-sulfonic acid
- English name
- 2-[(1-Oxo-5z,8z,11z,14z-eicosatetraenyl)amino]-ethane sulfonic acid
- Molecular formula
- C22H37NO4S
- Molecular weight
- 411.6
Names & synonyms
N-ARACHIDONOYL TAURINEN-Arachidonoyl Taurine Exclusive2-[(1-Oxo-5z,8z,11z,14z-eicosatetraenyl)amino]-ethane sulfonic acidEthanesulfonic acid, 2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]amino]-
Database identifiers
- CAS
119959-65-8- PubChem CID
- 42607331
- DTXSID
DTXSID701134033- ChEBI
CHEBI:132506- Nikkaji
- J2.355.716I
Properties
Physicochemical properties
- storage temp.
- -20 °C · Store at -20°C
- solubility
- 10 mg/ml; · DMF: 10 mg/ml; DMSO: 20 mg/ml; PBS (pH 7.2): 1.5 mg/ml
- form
- A crystalline solid
- color
- Light yellow to brown
Chemistry & industry
Applications
DescriptionN-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of Δ9-tetrahydrocannabinol (Δ9-THC).
UsesN-Arachidonoyltaurine is a polyunsaturated lipid that inhibits the Cav3.3 current in T-type calcium channels.
Suppliers13 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…