Basic information
- CAS
267402-71-1- Standard SMILES
COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c3ncn(C(C)C)c3n2)cc1- InChIKey
IDCOTQWQVPRTNK-UHFFFAOYSA-N- Molecular formula
- C24H28N6O2
- Average molar mass
- 432.5 g/mol
- Monoisotopic mass
- 432.22737416
Overview
a micotubule-binding molecule with cellular effects; structure in first source
Names & identifiers
- Preferred name
- Myoseverin
- IUPAC
- 2-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamine
- English name
- MYOSEVERIN
- Molecular formula
- C24H28N6O2
- Molecular weight
- 432.52
Names & synonyms
myoseverin267402-71-1RefChem:1603579-Isopropyl-N2,N6-bis(4-methoxybenzyl)-9H-purine-2,6-diamineMFCD026835962-N,6-N-bis[(4-methoxyphenyl)methyl]-9-propan-2-ylpurine-2,6-diamineSCHEMBL13325947HMS2043N15AKOS027326433CS-W009672SMP2_000092NCGC00165829-01
Show more names
Myoseverin>Myoseverin, 10 mM in DMSOMyoseverin - CAS 267402-71-1 - Calbiochem9-Isopropyl-2,6-bis(4-methoxybenzylamino)purine9H-Purine-2,6-diamine, N2,N6-bis[(4-methoxyphenyl)methyl]-9-(1-methylethyl)-Myoseverin,Microtubule/Tubulin,fragments,regeneration,tissue,inhibit,mononucleated,wound,Inhibitor,healing,microtubules,purine
AS-56244A123669H-Purine-2,6-diamine, N,N'-bis((4-methoxyphenyl)methyl)-9-(1-methylethyl)-CHEMBL141689orb1219465orb1306266orb3033152SXZ4Q2A633
Database identifiers
- CAS
267402-71-1
Properties
Computed structural properties
- XLogP
- 4.3
- Topological polar surface area
- 86.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 9
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 551
Physicochemical properties
- Melting point
- 106 to · 106.0 to 110.0 °C
- Boiling point
- 661.3 · 661.3±65.0 °C(Predicted)
- Density
- 1.24 · 1.24±0.1 g/cm3(Predicted)
- storage temp.
- 20 °C · −20°C
- solubility
- 50 mg/mL, · chloroform: 50 mg/mL, soluble
- form
- solid
- pka
- 4.65 · 4.65±0.30(Predicted)
- color
- off-white
- CAS DataBase Reference
- 267402 · 267402-71-1
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P280-P301+P312-P302+P352-P305+P351+P338
- WGK Germany
- 3 · 3
- HS Code
- 2933.99 · 2933.99.8290
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
- hs_code
- 2933.99.8290
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P280-P301+P312-P302+P352-P305+P351+P338
Chemistry & industry
Applications
UsesMyoseverin is a microtubule interfering agent resulting in adverse cellular function. It affects a variety of growth factor, immunomodulatory, extracellular matrix remodelling and stress-response genes. This activity is consistent with the activation of pathways involving tissue regeneration and healing.
Suppliers43 total
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
北京索莱宝科技有限公司010-50973130 17801761073 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
InvivoChem中国13549236410 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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