Diglycerin (HCID 42953)

Overview

Diglycerol is an alkylglycerol.

Names & identifiers

Preferred name: Diglycerin
IUPAC: 3-(2,3-dihydroxypropoxy)propane-1,2-diol
English name: DIGLYCEROL
Molecular formula: C6H14O5
Molecular weight: 166.17

Names & synonyms

DiglycerolDiglycerin3-(2,3-dihydroxypropoxy)propane-1,2-diol3YC120743U3-glyceryloxypropane-1,2-diolGlycerol dimerRESASSOL DNDIGLYCERIN 801GREAT OIL DI 1RefChem:1083566Beautyturess 80gTanning CreamDTXSID10891325

Show more names

Polyglycerol-2POLYGLYCERYL-2K-COL-IIDiglycerin S

Beautyturess 80g Shiny Tanning Cream261-605-559113-36-9627-82-73,3'-Oxybis(propane-1,2-diol)alpha,alpha'-DiglycerolDiglycerine1,2-Propanediol, 3,3'-oxybis-

Database identifiers

CAS: 59113-36-9、627-82-7
PubChem CID: 42953
DTXSID: DTXSID90872273
ChEBI: CHEBI:140430
UNII: UC0A740LR3
EC Number: 211-013-8
Nikkaji: J6.871C

Properties

Computed structural properties

XLogP: -2.5
Topological polar surface area: 90.2 Å²
Hydrogen bond donors: 4
Hydrogen bond acceptors: 5
Rotatable bonds: 6
Heavy atoms: 11
Formal charge: 0
Complexity: 77

Experimental & physicochemical properties

Cosmetics · 2 items

Cosmetic ingredients (Diglycerin) -> CIR (Cosmetic Ingredient Review)

Solvent; Humectant

SpringerMaterials PropertiesViscosity

Physical DescriptionLiquid

Physicochemical properties

Melting point: 96 · 96-97 °C
Boiling point: 173 °C · 173 °C(Press: 14 Torr)
Density: 1.2774 g/cm3 · 1.2774 g/cm3
vapor pressure: 0 Pa · 0Pa at 20℃
Viscosity: 17474 mm2/s · 17474mm2/s
Water Solubility: 1000 g/L · 1000g/L at 20℃
Cosmetics Ingredients Functions: HUMECTANTSKIN CONDITIONING
LogP: -2.5 at · -2.5 at 20℃
CAS DataBase Reference: 59113 · 59113-36-9
FDA UNII: 3 YC120743U · 3YC120743U
EPA Substance Registry System: Propanediol, oxybis- (59113-36-9)
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 302 · H302-H315-H319-H335
Precautionary statements: 280 · P280-P305+P351+P338
TSCA: TSCA listed
REACH Registrations: Active

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 25.3% (23 of 91) of reports.

Warning

H315 (74.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 91 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 3 items

Propanediol, oxybis- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Propanediol, oxybis- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.

1,2-Propanediol, 3,3'-oxybis-: Does not have an individual approval but may be used under an appropriate group standard

EPA Safer ChemicalChemical: Diglycerin

Hazard Classes and CategoriesSkin Irrit. 2 (74.7%)

Toxicology

Toxicity SummarySafe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org

Safety data

tsca: TSCA listed
Signal word: Warning
Symbol(GHS): GHS07
Hazard statements: H302-H315-H319-H335
REACH Registrations: Active
Precautionary statements: P280-P305+P351+P338

Chemistry & industry

Uses & manufacturing

UsesCIR ingredient: Diglycerin

U.S. Production2023: <50,000 lb

Industry UsesIntermediate

Household ProductsInformation on 1 consumer products that contain Diglycerol in the following categories is provided:

Use Classification · 3 items

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern

Cosmetics -> Solvent; Humectant

General Manufacturing Information · 2 items

Food, beverage, and tobacco product manufacturing

Propanediol, oxybis-: ACTIVE

Applications

DescriptionDiglycerol is soluble in water and is a colorless to light yellow liquid, which can be used as an intermediate in organic synthesis. It is mainly used for the preparation of fatty acid esters, used as emulsifiers and defoamers, etc.

UsesDiglycerol has excellent moisturizing properties and is a good water-based solvent. It can also be used as a moisturizing and moisturizing agent, softener, antifreeze agent, and can also be used in biodegradable plastics.