Basic information
- CAS
149231-65-2- Standard SMILES
CC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1)C(C)C- InChIKey
YGLOALWHJIANIH-UHFFFAOYSA-N- Molecular formula
- C33H39N5O10
- Average molar mass
- 665.7 g/mol
- Monoisotopic mass
- 665.26969245
Names & identifiers
- Preferred name
- Ac-YVAD-AMC
- IUPAC
- 3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxochromen-7-yl)amino]-4-oxobutanoic acid
- English name
- AC-YVAD-AMC
- Molecular formula
- C33H39N5O10
- Molecular weight
- 665.69
Names & synonyms
Ac-YVAD-AMC149231-65-2DTXSID20274428RefChem:313833DTXCID90225907Ac-Tyr-Val-Ala-Asp-MCAC33H39N5O10MAY-3161-VDB-042979N-Acetyl-Tyr-Val-Ala-Asp-7-amido-4-methylcoumarinAcetyl-L-Tyrosyl-L-Valyl-L-Alanyl-L-Aspartic Acid ?-(4-Methyl-Coumaryl-7-Amide)N-Acetyltyrosylvalylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-alpha-asparagine
Show more names
AC-YVAD-MCAACETYL-YVAD-AMCICE SUBSTRATE IIICaspase-1 fluoroAC-YVAD-AMC USP/EP/BPAC-TYR-VAL-ALA-ASP-AMCCASPASE I SUBSTRATE IIIN-Ac-Tyr-Val-Ala-Asp-AMC
3-[2-[[2-[[2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methyl-butanoyl]amino]propanoylamino]-4-[(4-methyl-2-oxo-chromen-7-yl)amino]-4-oxo-butanoic acid
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 1.3
- Topological polar surface area
- 229 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 14
- Heavy atoms
- 48
- Formal charge
- 0
- Complexity
- 1,260
Physicochemical properties
- Boiling point
- 1127.307 · 1127.307±65.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.344 · 1.344±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- 20 °C · −20°C
- solubility
- 10 mM · DMSO: 10 mM The solution is stable in the dark at −20 °C for more than 1 month if no water is present.
- pka
- 4.095 · 4.095±0.10(predicted)
- form
- powder
- color
- white
- Sequence
- Ac-Tyr-Val-Ala-Asp-AMC
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Applications
UsesAc-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells[1].
Suppliers49 total
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
VDM Biochemicals0330-2528181 · [email protected]
Chengdu Youngshe Chemical Co., Ltd.+86-18108235634 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
LEON (NANJING) BIOTECHNOLOGY CO., LTD.15051830413 · [email protected]
Moxin Chemicals+86-17320513646 +86-17320513646 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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