Basic information
- CAS
59880-97-6- Standard SMILES
CSCCC(NC=O)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)O- InChIKey
PRQROPMIIGLWRP-UHFFFAOYSA-N- Molecular formula
- C21H31N3O5S
- Average molar mass
- 437.6 g/mol
- Monoisotopic mass
- 437.19844227
Overview
2-[[2-[[2-formamido-4-(methylthio)-1-oxobutyl]amino]-4-methyl-1-oxopentyl]amino]-3-phenylpropanoic acid is a peptide.
Names & identifiers
- Preferred name
- N-Formylmethionine Leucyl-Phenylalanine
- IUPAC
- 2-[[2-[(2-formamido-4-methylsulfanylbutanoyl)amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
- English name
- Tyramine hydrochloride
- Molecular formula
- C21H31N3O5S
- Molecular weight
- 437.55
Names & synonyms
N-FORMYLMETHIONINE LEUCYL-PHENYLALANINEFormylmet Leu PheFormylmet-Leu-PhePeptide, FormylmethionylRefChem:927168FormylmethionylleucylphenylalanineFormylmethionyl Leucyl PhenylalanineFormylmethionyl-Leucyl-PhenylalanineN formylmethionyl leucyl phenylalanineN Formylmethionine Leucyl PhenylalanineLeucyl-Phenylalanine, N-FormylmethionineN Formyl Methionyl Leucyl Phenylalanine
Show more names
fMLFTYRAMINE HCLfMLF, fMLPNSC 350593F-MET-LEU-PHETYROSAMINE HCLTYRAMINE HCL(P)TYRAMINE HCL(RG)TIMTEC-BB SBB003808N-Formyl-Met-Leu-Phe-OH
N-FORMYLMETHIONYL-LEUCYLPHENYLALANINEChemotactic peptideC21H31N3O5SfMLP;N-Formyl-MLF2-{2-[2-formamido-4-(methylsulfanyl)butanamido]-4-methylpentanamido}-3-phenylpropanoic acidLO6AVJ8RCEFor-Met-Leu-PheUNII-LO6AVJ8RCE
Properties
Computed structural properties
- XLogP
- 1.5
- Topological polar surface area
- 150 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 13
- Heavy atoms
- 30
- Formal charge
- 0
- Complexity
- 567
Physicochemical properties
- Melting point
- 271 · 271-274 °C(lit.)
- Boiling point
- 269 °C · 269 °C
- Density
- 1.198 · 1.198±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C
- solubility
- 50 mg/mL, · DMF: 50 mg/mL, clear, colorless
- pka
- 3.5 · 3.50±0.10(Predicted)
- form
- White to off-white lyophilized solid
- color
- White to Almost white
- BRN
- 2315783 · 2315783
- Sequence
- N-Formyl-Met-Leu-Phe-OH
- Major Application
- cell analysis
- InChIKey
- PRQROPMIIGLWRP-BZSNNMDCSA-N
- SMILES
- C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O
- CAS DataBase Reference
- 59880 · 59880-97-6(CAS DataBase Reference)
- FDA UNII
- 6 AVJ8RCE · LO6AVJ8RCE
- UNSPSC Code
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- F
- 3-10
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- rtecs
- SJ6050000
- hs_code
- 2930.90.9250
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36-22
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesInduces leucocyte chemotaxis, and activates macrophages
UsesN-Formyl-Met-Leu-Phe has been used for:creating gradients in Zigmond chamber chemotaxis assay performed on neutrophilsuse in neutrophil chemotaix assay anddetermination of the involvement of MAPK-activating protein kinase-2 (MAPKAPK-2) and/or p38, in the signaling pathway of human polymorphonuclear leukocytes (PMNs) stimulated by N-Formyl-Met-Leu-Phe.
General DescriptionN-Formyl-Met-Leu-Phe is a chemotactin peptide, which functions on polymorphonuclear leukocytes (PMN), neutrophils etc.
Suppliers99 total
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
上海莉凯化工技术有限公司16628776521 · [email protected]
上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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