Arg-Arg-Arg
Basic information
- CAS
26982-20-7- Standard SMILES
NC(N)=NCCC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCCN=C(N)N)C(=O)O- InChIKey
XPSGESXVBSQZPL-SRVKXCTJSA-N- Molecular formula
- C18H38N12O4
- Average molar mass
- 486.6 g/mol
- Monoisotopic mass
- 486.31389774
Overview
Arg-Arg-Arg is a tripeptide.
Names & identifiers
- Preferred name
- Arg-Arg-Arg
- IUPAC
- (2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
- English name
- Poly-L-arginine hydrochloride
- Molecular formula
- C6H14N4O2
- Molecular weight
- 174.2
Names & synonyms
Arg-Arg-ArgL-Arginyl-L-arginyl-L-arginineRefChem:1077174arginyl-arginyl-arginine6418-87-7(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acidCHEMBL1269805SCHEMBL29462955CHEBI:158723DTXSID101369662FA108536C01952
Show more names
POLY-L-ARGININE HCLmw10000-20000Arg dihydrochloridePoly-L-Arg HCl MW=29KDaPoly-L-Arg HCl MW=1.9KDaPoly-L-Arg HCl MW=9.6KDaPoly-L-Arg HCl MW=5.8KDaPoly-L-Arg HCl MW=38.5KDaPoly-L-arginine hydrochloridePOLY-L-ARGININE HYDROCHLORIDE MOL. W
(S)-2-((S)-2-((S)-2-Amino-5-guanidinopentanamido)-5-guanidinopentanamido)-5-guanidinopentanoic acid
Properties
Computed structural properties
- XLogP
- -8.5
- Topological polar surface area
- 315 Ų
- Hydrogen bond donors
- 10
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 17
- Heavy atoms
- 34
- Formal charge
- 0
- Complexity
- 743
Physicochemical properties
- storage temp.
- -20 °C · -20°C
- form
- powder or solid
- color
- white to off-white
- Major Application
- cell analysis
- Cosmetics Ingredients Functions
- NAIL CONDITIONING
- InChI
- InChI=1/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/s3
- InChIKey
- ODKSFYDXXFIFQN-UFLUHPNLNA-N
- SMILES
- C([C@H](N)C(=O)O)CCNC(N)=N |&1:1,r|
- UNSPSC Code
- 12352209 · 12352209
- NACRES
- 26 · NA.26
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- WGK Germany
- 3 · 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesPoly-L-arginine hydrochloride has been used:as polyelectrolyte solution in the synthesis of biodegradable capsulesas layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shellsin assay for the determination of binding activity of C-reactive protein for polycationic ligands
UsesPoly-L-arginine hydrochloride has been used:to generate complex with stimulatory RNA isRNA9.2 as in neutrophilsused in ribosomal RNA transfection into human monocytic THP-1 cellsfor coating alginate capsule beads
General DescriptionPoly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality.
Related reactions
0 records
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Compound notes
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