Alnert
Basic information
- CAS
62232-46-6- Standard SMILES
C[NH2+]CCCCOc1ccccc1Cc1ccccc1.[Cl-]- InChIKey
MEAHDXWXNNDSAK-UHFFFAOYSA-N- Molecular formula
- C18H24ClNO
- Average molar mass
- 305.8 g/mol
- Monoisotopic mass
- 305.1546421
Overview
Bifemelane hydrochloride is a diarylmethane.
Names & identifiers
- Preferred name
- Alnert
- IUPAC
- 4-(2-benzylphenoxy)butyl-methylazanium chloride
- English name
- Bifemelane HCl
- Molecular formula
- C18H23NO.ClH
- Molecular weight
- 305.847
Names & synonyms
AlnertCeleportBifemelane hydrochloride [JAN]4-(2-benzylphenoxy)butyl-methylazanium;chlorideE-0687Bifemelane hydrochloride (JAN)UNII-2N52S01UFYButylamine, N-methyl-4-(o-benzylphenoxy)-, hydrochlorideCHEBI:31285NS00124795D01793Bifemelane HCl
Show more names
Bifemelan hydrochlorideBifemelane hydrochlorideMEAHDXWXNNDSAK-UHFFFAOYSA-NBifemelane hydrochloride, 10 mM in DMSO4-(2-Benzylphenoxy)-N-methylbutan-1-amine hydrochlorideN-Methyl-4-[2-(phenylmethyl)phenoxy]-1-butanamine hydrochlorideinhibit,Inhibitor,Monoamine Oxidase,MAO-A,MAO,MCI 2016,Bifemelane hydrochloride,antidepressant,Bifemelane,monoamine,MCI-2016,MCI2016,oxidase,MAO-B
Database identifiers
- CAS
62232-46-6- PubChem CID
- 43962
- ChEBI
CHEBI:31285
Properties
Computed structural properties
- Topological polar surface area
- 25.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 8
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 238
Physicochemical properties
- Melting point
- 117 · 117-121°
- solubility
- 100 mM · Soluble to 100 mM in water and to 100 mM in DMSO
- form
- Powder
- color
- White to yellow
- FDA UNII
- 2 N52S01UFY · 2N52S01UFY
- Toxicity
- 50 in · LD50 in mice, rats (mg/kg): 1000, 1080 orally; 173, 130 i.p. (Tobe, 1981)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- LD50 in mice, rats (mg/kg): 1000, 1080 orally; 173, 130 i.p. (Tobe, 1981)
Chemistry & industry
Applications
DescriptionBifemelane is a nootropic reported to have antianoxic, anti-ischemic and memory enhancing activities. In man, bifemelane appears to increase cerebral blood flow, while in rodents it reverses scopolamine-induced dementia. Bifemelane has an added adrenergic component reportedly arising from norepinephrine uptake inhibition.
UsesBifemelane Hydrochloride, is an antidepressant MAO inhibitor. It has also been reported to protect neural tissues against ischemic damage and age-related neurodegeneration.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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