CAS 2799-16-8 (2R)-1-aminopropan-2-ol (HCID 439938)

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Basic information

CAS: 2799-16-8
Standard SMILES: C[C@@H](O)CN
InChIKey: HXKKHQJGJAFBHI-GSVOUGTGSA-N
Molecular formula: C3H9NO
Average molar mass: 75.11 g/mol
Monoisotopic mass: 75.06841391

Overview

(2R)-1-aminopropan-2-ol is a 1-aminopropan-2-ol that has R-configuration. It is a conjugate base of a (2R)-2-hydroxypropylammonium.

Names & identifiers

Preferred name: (2R)-1-aminopropan-2-ol
IUPAC: (2R)-1-aminopropan-2-ol
English name: (R)-(-)-1-Amino-2-propanol
Molecular formula: C3H9NO
Molecular weight: 75.11

Names & synonyms

(R)-(-)-1-Amino-2-propanol(R)-1-Amino-2-propanol(2R)-1-aminopropan-2-ol(R)-(-)-1-Aminopropan-2-ol2-Propanol, 1-amino-, (2R)-(2R)-(-)-hydroxypropylamine(2R)-(-)-2-hydroxypropylamineEINECS 220-532-9CHEBI:15675DTXSID101318940RefChem:396846DTXCID701744452

Show more names

(R)-2-Aminopropan-1-olISOPROPANOLAMINEIsopropanolaminR-l-Amino-2-propanol(R)-1-Aminopropane-2-ol(R)-(-)-ISOPROPANOLAMINE

220-532-92799-16-8(R)-1-aminopropan-2-ol(2R)-1-amino-2-propanolMFCD00064428(2~{R})-1-azanylpropan-2-ol(-)-Isopropanolamine1-Amino-2-propanol #

Database identifiers

CAS: 2799-16-8
PubChem CID: 439938
DTXSID: DTXSID101318940
ChEBI: CHEBI:15675
EC Number: 220-532-9

Properties

Computed structural properties

XLogP: -1
Topological polar surface area: 46.3 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 2
Rotatable bonds: 1
Heavy atoms: 5
Formal charge: 0
Complexity: 22.9

Experimental & physicochemical properties

SpringerMaterials PropertiesBoiling point

Physicochemical properties

Melting point: 24 · 24-26 °C (lit.)
alpha: -18 · -18 º (c=1.8, H2O)
Boiling point: 160 °C · 160 °C (lit.)
Density: 0.954 g/mL · 0.954 g/mL at 25 °C (lit.)
vapor density: 2.6 · 2.6 (vs air)
vapor pressure: 1 mm · <1 mm Hg ( 20 °C)
refractive index: 20 · n20/D 1.4482(lit.)
Flash point: 165 °F · 165 °F
storage temp.: 2 · Keep in dark place,Inert atmosphere,2-8°C
form: Liquid After Melting
pka: 12.92 · 12.92±0.35(Predicted)
color: Clear colorless to light yellow

Safety & regulation

GHS classification

GHS Classification · 4 items

Danger

H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 82 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information(R)-(-)-1-Amino-2-propanol: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Corr. 1B (100%)

Safety data

F: 10-34
PPE: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
wgk: 1
rtecs: UA5775000
ridadr: UN 3259 8/PG 2
hs_code: 29221990
risk_code: 34
Signal word: Danger
Symbol(GHS): GHS05
hazard_code: C
safety_code: 23-26-36-45
hazard_class: 8
Storage Class: 8A - Combustible corrosive hazardous materials
packing_group: III
Hazard statements

Chemistry & industry

Applications

Uses(R)-(-)-1-Amino-2-propanol is a useful research intermediate used in the synthesis of other bioactive small molecules with pharmaceutical applications.