Acetyl-Ser-Asp-Lys-Pro
Basic information
- CAS
127103-11-1- Standard SMILES
CC(=O)NC(CO)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)O- InChIKey
HJDRXEQUFWLOGJ-UHFFFAOYSA-N- Molecular formula
- C20H33N5O9
- Average molar mass
- 487.5 g/mol
- Monoisotopic mass
- 487.22782765
Names & identifiers
- Preferred name
- Acetyl-Ser-Asp-Lys-Pro
- IUPAC
- 1-[2-[[2-[(2-acetamido-3-hydroxypropanoyl)amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid
- English name
- Goralatide
- Molecular formula
- C20H33N5O9
- Molecular weight
- 487.5
Names & synonyms
Acetyl-Ser-Asp-Lys-Pro127103-11-1DTXSID30402957RefChem:317007DTXCID103538121-[2-[[2-[(2-acetamido-3-hydroxypropanoyl)amino]-3-carboxypropanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acidGoralatide?MFCD00076849C20H33N5O9Acetyl-serinyl-aspartyl-lysinyl-prolineSCHEMBL30148825N-Acetylseryl-alpha-aspartyllysylproline
Show more names
AC-SDKPSERASPENIDEThymosin β4 (1-4)Acetyl-SDKPAC-SER-ASP-LYS-PROAC-SER-ASP-LYS-PRO-OHGORALATIDEAC-SDKP-DELTAThymosin beta4 (1-4)AC-SER-ASP-LYS-PRO-O
Acetyl-Ser-Asp-Lys-Pro, >=97% (HPLC)1-[2-[[2-[(2-acetamido-3-hydroxy-propanoyl)amino]-3-carboxy-propanoyl]amino]-6-amino-hexanoyl]pyrrolidine-2-carboxylic acid
Database identifiers
- CAS
127103-11-1- PubChem CID
- 4409396
- DTXSID
DTXSID30402957
Properties
Computed structural properties
- XLogP
- -5.4
- Topological polar surface area
- 228 Ų
- Hydrogen bond donors
- 7
- Hydrogen bond acceptors
- 10
- Rotatable bonds
- 14
- Heavy atoms
- 34
- Formal charge
- 0
- Complexity
- 776
Physicochemical properties
- Boiling point
- 992 · 992.0±65.0 °C(predicted)
- Density
- 1.382 · 1.382±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
- storage temp.
- 20 °C · −20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 3.39 · 3.39±0.20(predicted)
- color
- White to off-white
- Water Solubility
- 2 mg/ml · Soluble in water at 2mg/ml
- Sequence
- H-Gln-Lys-Leu-Val-Phe-Phe-Ala-OH
- FDA UNII
- 41538 E9P · H041538E9P
- WGK Germany
- 3 · 3
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 3
Chemistry & industry
Applications
UsesN-Acetyl-Ser-Asp-Lys-Pro inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice. It is a specific substrate for the N-terminal active site of angiotensin converting enzyme, which is responsible for its degradation in vivo.
Related reactions
0 records
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Compound notes
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