Hydroxyamine hydrochloride

HCID 443297CAS 5470-11-1

Basic information

Standard SMILES
Cl.NO
InChIKey
WTDHULULXKLSOZ-UHFFFAOYSA-N
Molecular formula
ClH.H3NO
Average molar mass
69.49 g/mol

Overview

Hydroxylamine hydrochloride appears as colorless or off-white crystalline solid. pH (0.1 molar aqueous solution) 3.4. pH (0.2 molar aqueous solution) 3.2. (NTP, 1992)

Names & identifiers

Preferred name
Hydroxyamine hydrochloride
IUPAC
hydroxylamine;hydrochloride

Names & synonyms

Hydroxylamine hydrochloride5470-11-1Hydroxylammonium chlorideOxammonium hydrochlorideHydroxyamine hydrochlorideHydroxylamine chloride (1:1)NSC-262505X4ZA62Z4QHYDROXYLAMINE CHLOROHYDRATERefChem:5895226-798-2DTXCID501476239
Show more names
DTXSID7025425Hydroxyammonium chlorideHydroxylamine chlorideHYDROXYLAMINE, HYDROCHLORIDEhydroxylamine;hydrochlorideMFCD00051089hydroxyl amine hydrochlorideHydroxyamine (hydrochloride)

Database identifiers

CAS
5470-11-1
PubChem CID
443297
ChEMBL
CHEMBL542448
ChEBI
CHEBI:5807
UNII
5X4ZA62Z4Q
EC Number
226-798-2

Properties

Computed structural properties

Topological polar surface area
46.3 Ų
Hydrogen bond donors
3
Hydrogen bond acceptors
2
Rotatable bonds
0
Heavy atoms
3

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Hydroxylamines
Density · 3 items

1.67 at 63 °F (NTP, 1992) - Denser than water; will sink

1.7 g/cm³

1.6717 @25 °C

Solubility · 2 items

greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)

Solubility in water, g/100ml at 25 °C: 94 (freely soluble)

Boiling PointDecomposes (NTP, 1992)
Melting Point · 3 items

304 °F (Decomposes) (NTP, 1992)

304 °F (decomposes)

154 °C

Physical Description · 3 items

Hydroxylamine hydrochloride appears as colorless or off-white crystalline solid. pH (0.1 molar aqueous solution) 3.4. pH (0.2 molar aqueous solution) 3.2. (NTP, 1992)

Colorless to off-white crystals that are hygroscopic and water soluble; [CAMEO]

COLOURLESS HYGROSCOPIC CRYSTALS.

Safety & regulation

GHS classification

GHS Classification · 6 items

Warning

H290: May be corrosive to metals [Warning Corrosive to Metals]

P203, P234, P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P391, P405, P406, and P501 (click each P-code to see the statement)

Warning

H290 (99.8%): May be corrosive to metals [Warning Corrosive to Metals]

P203, P234, P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P391, P405, P406, and P501 (click each P-code to see the statement)

Hazard information

Regulatory Information · 3 items

Chemical: Hydroxylamine, hydrochloride

Status: Active Update: 18-11-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/24099

Hydroxylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Hydroxylamine and its salts: Human health tier II assessment
DOT LabelCorrosive Poison
Fire Hazards · 2 items

Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)

Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of explosion as a result of decomposition when heated.

Health Hazards · 1 item

SYMPTOMS: Symptoms of exposure to this chemical include eye, skin and mucous membrane irritation; burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, vomiting and methemoglobinemia. Inhalation may be fatal as a result of spasm, inflammation and edema of the larynx and bronchi; chemical pneumonitis and pulmonary edema.

Hazards Summary · 1 item

A powerful reducing agent and a strong irritant of the skin and eyes; Can cause methemoglobinemia; Inhalation of high concentrations can induce toxic pneumonitis; [CAMEO] Negligible evaporation at room temperature; Harmful if dispersed particles are inhaled; A skin sensitizer; [ICSC] Causes skin burns; [MSDSonline] See Hydroxylamine.

Safety & protection

Fire Fighting · 2 items

Fires involving this material can be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

In case of fire in the surroundings, use appropriate extinguishing media.

First Aid Measures · 4 items

Fresh air, rest. Refer for medical attention.

Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Safe StorageDry. Cool. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.
Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Spillage Disposal · 1 item

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Toxicology

Adverse EffectsMethemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect
Exposure RoutesThe substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.
Signs and Symptoms · 4 items

Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Confusion. Convulsions. Unconsciousness.

MAY BE ABSORBED! Redness. Pain. Further see Inhalation.

Redness. Pain.

See Inhalation.

ICSC Environmental DataThe substance is very toxic to aquatic organisms.

Chemistry & industry

Uses & manufacturing

Uses · 2 items

Hydroxylamine is used in organic synthesis; in photographic developers; in the production of rubber, plastics, and steel; and in the separation of uranium and plutonium; [Ullmann]

Steel Producing [Category: Industry]

General Manufacturing InformationHydroxylamine, hydrochloride (1:1): ACTIVE

Related reactions

7,871 records

Linked notes

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