Basic information
- Standard SMILES
Cl.NO- InChIKey
WTDHULULXKLSOZ-UHFFFAOYSA-N- Molecular formula
- ClH.H3NO
- Average molar mass
- 69.49 g/mol
Overview
Hydroxylamine hydrochloride appears as colorless or off-white crystalline solid. pH (0.1 molar aqueous solution) 3.4. pH (0.2 molar aqueous solution) 3.2. (NTP, 1992)
Names & identifiers
- Preferred name
- Hydroxyamine hydrochloride
- IUPAC
- hydroxylamine;hydrochloride
Names & synonyms
Show more names
Database identifiers
- CAS
5470-11-1- PubChem CID
- 443297
- ChEMBL
CHEMBL542448- ChEBI
CHEBI:5807- UNII
- 5X4ZA62Z4Q
- EC Number
- 226-798-2
Properties
Computed structural properties
- Topological polar surface area
- 46.3 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 3
- Formal charge
- 0
- Complexity
- 2
Experimental & physicochemical properties
Density
1.67 at 63 °F (NTP, 1992) - Denser than water; will sink
1.7 g/cm³
1.6717 @25 °C
Solubility
greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
Solubility in water, g/100ml at 25 °C: 94 (freely soluble)
Melting Point
304 °F (Decomposes) (NTP, 1992)
304 °F (decomposes)
154 °C
Physical Description
Hydroxylamine hydrochloride appears as colorless or off-white crystalline solid. pH (0.1 molar aqueous solution) 3.4. pH (0.2 molar aqueous solution) 3.2. (NTP, 1992)
Colorless to off-white crystals that are hygroscopic and water soluble; [CAMEO]
COLOURLESS HYGROSCOPIC CRYSTALS.
Safety & regulation
GHS classification
GHS Classification
Warning
H290: May be corrosive to metals [Warning Corrosive to Metals]
P203, P234, P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P391, P405, P406, and P501 (click each P-code to see the statement)
Warning
H290 (99.8%): May be corrosive to metals [Warning Corrosive to Metals]
P203, P234, P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P390, P391, P405, P406, and P501 (click each P-code to see the statement)
Hazard information
Regulatory Information
Chemical: Hydroxylamine, hydrochloride
Status: Active Update: 18-11-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/24099
Hydroxylammonium chloride: Does not have an individual approval but may be used under an appropriate group standard
Fire Hazards
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. Risk of explosion as a result of decomposition when heated.
Health Hazards
SYMPTOMS: Symptoms of exposure to this chemical include eye, skin and mucous membrane irritation; burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, vomiting and methemoglobinemia. Inhalation may be fatal as a result of spasm, inflammation and edema of the larynx and bronchi; chemical pneumonitis and pulmonary edema.
Hazards Summary
A powerful reducing agent and a strong irritant of the skin and eyes; Can cause methemoglobinemia; Inhalation of high concentrations can induce toxic pneumonitis; [CAMEO] Negligible evaporation at room temperature; Harmful if dispersed particles are inhaled; A skin sensitizer; [ICSC] Causes skin burns; [MSDSonline] See Hydroxylamine.
Safety & protection
Fire Fighting
Fires involving this material can be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
In case of fire in the surroundings, use appropriate extinguishing media.
First Aid Measures
Fresh air, rest. Refer for medical attention.
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Nonfire Spill Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Spillage Disposal
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered non-metallic containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.
Toxicology
Signs and Symptoms
Blue lips, fingernails and skin. Headache. Dizziness. Nausea. Confusion. Convulsions. Unconsciousness.
MAY BE ABSORBED! Redness. Pain. Further see Inhalation.
Redness. Pain.
See Inhalation.
Chemistry & industry
Uses & manufacturing
Uses
Hydroxylamine is used in organic synthesis; in photographic developers; in the production of rubber, plastics, and steel; and in the separation of uranium and plutonium; [Ullmann]
Steel Producing [Category: Industry]
Related reactions
Linked notes
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