Terazosin Hydrochloride Anhydrous

HCID 44383

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Basic information

CAS: 63074-08-8
Standard SMILES: COc1cc2nc(N3CCN(C(=O)C4CCCO4)CC3)nc(N)c2cc1OC.Cl
InChIKey: IWSWDOUXSCRCKW-UHFFFAOYSA-N
Molecular formula: C19H26ClN5O4
Average molar mass: 423.9 g/mol
Monoisotopic mass: 423.16733199

Overview

See also: Terazosin (has active moiety); Terazosin Hydrochloride (annotation moved to).

Names & identifiers

Preferred name: Terazosin Hydrochloride Anhydrous
IUPAC: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;hydrochloride

Names & synonyms

63074-08-8Terazosin HClTerazosin hydrochloride anhydrousPiperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-, monohydrochloride8QOP8Z9955ABBOTT-45975 ANHYDROUSRefChem:932721613-138-7HytrinVasocard(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone hydrochlorideMLS000040261

Show more names

Terazosin (hydrochloride)ZayaselMFCD004679656,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloridePiperazine,1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, monohydrochlorideSMR000044015Prazosin Tetrahydro Impurity1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride

Database identifiers

CAS: 63074-08-8、70024-40-7
PubChem CID: 44383
DTXSID: DTXSID7045493
ChEMBL: CHEMBL1256665
UNII: 8QOP8Z9955
EC Number: 613-138-7

Properties

Computed structural propertiesFilling in

Topological polar surface area: 103 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 8
Rotatable bonds: 4
Heavy atoms: 29
Formal charge: 0
Complexity: 544

Experimental & physicochemical properties

Collision Cross Section195.7 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.

Warning

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

P203, P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P318, P330, P337+P317, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.