Basic information
- CAS
188247-01-0- Standard SMILES
Cc1cc(N(C)C)ccc1-c1nc2ccc(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)cc2[nH]1- InChIKey
ADKLMOJIJGHCCD-UHFFFAOYSA-N- Molecular formula
- C28H31N7
- Average molar mass
- 465.6 g/mol
- Monoisotopic mass
- 465.26409402
Overview
a radioprotective agent; structure in first source
Names & identifiers
- Preferred name
- Methylproamine
- IUPAC
- N,N,3-trimethyl-4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]aniline
- English name
- MethylproaMine
- Molecular formula
- C28H31N7
- Molecular weight
- 465.59
Names & synonyms
Methylproamine188247-01-0DTXSID80332275RefChem:158297DTXCID30283369N,N,3-trimethyl-4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]anilineN,N,3-Trimethyl-4-(5-(4-methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)aniline2'-(3-METHYL-4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLEBenzenamine, N,N,3-trimethyl-4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-N,N,3-trimethyl-4-{6-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1H-1,3-benzodiazol-2-yl}anilineMFCD25976766CS-1306
Show more names
Methylproamine, >99%Methylproamine, 10 mM in DMSOInhibitor,Radioprotector,DNA/RNA Synthesis,Methylproamine,inhibit,DNA double-strand
orb1309428SCHEMBL16488402C28H31N7EX-A11260MFCD30738246AKOS037643718AS-3282NCGC00390626-01
Properties
Computed structural properties
- XLogP
- 4.8
- Topological polar surface area
- 67.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 4
- Heavy atoms
- 35
- Formal charge
- 0
- Complexity
- 709
Physicochemical properties
- Boiling point
- 746.8 · 746.8±70.0 °C(Predicted)
- Density
- 1.262 · 1.262±0.06 g/cm3(Predicted)
- solubility
- 25 ℃: · 25℃: DMSO
- form
- Powder
- pka
- 10.97 · 10.97±0.10(Predicted)
- color
- Light yellow to pink
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
UsesMethylproamine is a DNA-binding radioprotector, acts by repair of transient radiation-induced oxidative species on DNA. Methylproamine also protects against ionizing radiation by preventing DNA double-strand breaks[1].
Suppliers29 total
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
北京博奥森生物技术有限公司400-901-9800 18611424007 · [email protected]
MedChemexpress LLC021-58955995 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
Henan Alfa Chemical Co., Ltd+8618339805032 · [email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海阿拉丁生化科技股份有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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