Basic information
- Standard SMILES
CCCOc1cc([C@]2(C)CNC(=O)O2)ccc1OC- InChIKey
PCCPERGCFKIYIS-AWEZNQCLSA-N- Molecular formula
- C14H19NO4
- Average molar mass
- 265.3 g/mol
- Monoisotopic mass
- 265.13140809
Overview
a potent & selective type IV phosphodiesterase inhibitor
Names & identifiers
- Preferred name
- Mesopram
- IUPAC
- (5R)-5-(4-methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one
- English name
- mesopram
- Molecular formula
- C14H19NO4
- Molecular weight
- 265.3
Names & synonyms
MesopramDaxalipram189940-24-7(5R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-1,3-oxazolidin-2-one0RB5T277IYSH636SH-636ZK117137ZK-117137DTXSID001319171RefChem:131031DTXCID401748598
Show more names
SH 636ZK 117137(R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone(R)-5-(4-methoxy-3-propoxyphenyl)-5-methyloxazolidin-2-one(5R)-5-(4-Methoxy-3-propoxyphenyl)-5-Methyl-2-oxazolidinone2-Oxazolidinone, 5-(4-methoxy-3-propoxyphenyl)-5-methyl-, (5R)-
5-(methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone(R)-MESOPRAM[R]-MesopramDaxalipram [INN]CHEMBL603830Daxalipram; SH 636; ZK 1171371xm6DAXALIPRAM [WHO-DD]
Database identifiers
- CAS
189940-24-7- PubChem CID
- 449190
- DTXSID
DTXSID001319171- ChEMBL
CHEMBL603830- UNII
- 0RB5T277IY
- Nikkaji
- J2.834.017F
Properties
Computed structural properties
- XLogP
- 2.3
- Topological polar surface area
- 56.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 5
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 323
Experimental & physicochemical properties
DrugsPharmaceuticals -> Listed in ZINC15
Endocrine DisruptorsPotential endocrine disrupting compound
Physicochemical properties
- Boiling point
- 459.1 · 459.1±45.0 °C(Predicted)
- Density
- 1.124 · 1.124±0.06 g/cm3(Predicted)
- storage temp.
- 4 °C · Store at +4°C
- solubility
- 26.53 mg/ml · <26.53mg/ml in DMSO; <26.53mg/ml in ethanol
- pka
- 12.23 · 12.23±0.40(Predicted)
- form
- Solid
- color
- White to off-white
- FDA UNII
- 0 RB5T277IY · 0RB5T277IY
Chemistry & industry
Applications
UsesMesopram is an orally active phosphodiesterase (PDE) 4 inhibitor. Mesopram decreases the synthesis of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ). Mesopram is used in compositions for the treatment or prevention of respiratory inflammation.
Suppliers15 total
Aladdin Scientific[email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
苏州美石生物科技有限公司1173954148q · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
EMMX Biotechnology LLC888-539-0666 · [email protected]
深圳聚合生化科技有限公司+86-400-002-6226 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
北京百灵威科技有限公司18210857532 18210857532 · [email protected]
南京世洲生物科技有限公司025-85560043 13675144456 · [email protected]
山东子易医药有限公司13173053288 · [email protected]
Related reactions
1 records
Linked notes
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